Hello all. My ALP responded quickly to URSO when I was diagnosed in 2014. I started having pain again off and on and lately more on. I have had three surgeries in the last year. My thyroid removed for cancer, a fibroid removed with a ovary and an emergency removal of the other ovary. The last one I had a ton of intravenous pain meds. I was going to start taking a hormone patch for my menopause and I had blood drawn prior to make sure what was going on with my liver and my alp, which as has been stable at around 170 to 180 since I started on URSO spiked to 290 and my filtration rate on my kidneys dropped from 90 to 70. I also had a small lesion on my liver found on a CT in the hospital that said "Too small to characterize" likely a cyst. Low density lesion. So now I am scared that the jump in the ALP is due to this lesion being cancer, at worst, or my PBC has stopped responding already after just two years. I knew that I would eventually have issues, but after just two years? Or can the ALP just be responding to all the surgeries I have had? It had recovered from the first two surgeries and the ALP hadn't gone up, but this last one was an emergency surgery and they weren't as careful with the liver because they were just trying to save my life.
Questions: If it was cancer, would the ALP be even higher? I'm waiting on my doctor to call me back. He was sent all these test results from my OBGYN. I hadn't sent him the CT scan yet either, as I had read that al small lesion like that is not usually anything. But now I am having the pain on the right side in the back where they said that lesion was. But I know it could be the PBC too, as I have always had pain and aching off and on with the PBC, but much much less after I went on meds. Just very upset tonight. I also heard that its very uncommon to get liver cancer unless you are in cirrhosis. I, as far as I know, am not in cirrhosis. I am waiting on the tests to become available online to see what the bilirubin and albumin are as well. I know that would be a sign of the liver getting worse too.