I went to gastro this week and was given a higher dose of urso. My ALP has been rising instead of lowering or leveling. She also gave me a higher dose of hydroxyzine for the itching. I have been on vit D for a month now. I still have constant muscle and joint pain. Does anyone know how long it takes for the Vit D to start helping or the urso? The fatigue is really kicking my behind. I can't seem to get anything done, can't remember things and everyone (friends and family) seems to think I am just making things up. I am feeling so frustrated. Hope everyone one is well. Thanks for listening.