Using up my B1 Thiamine.

[WIZARD6787]

I never got the hang of knowing when I used up my B12 as some experience. Likely as I was also B1 deficient. The only way to determine if you are B1 deficient is to do a trial. The blood test is useless.

Functional Deficiency of a Vitamin may be nothing more than a work around for not understanding that some organs can be deficient and the testing is inadequate to determine that and the only way is with a trial based on symptoms.

I have not experienced what I knew as fatigue/brain fog since I started injecting three times a day and taking sublingual Adeno . I now experience what I term brain haze/being off. That has improved dramatically in the last 14 days I have been taking 50 mg P-5-P and 300 mg Benfotiamine B1 three times a day.

When I started this post I was thinking I sometimes use up my B1 between doses. That does happen but in this moment I think my getting slightly was not from getting more sun and my body adjusting to the B1 and beleve t is from under supplementing B1. I am more and more leaning towards reversing out and the paradox of feeling worse is due to under supplementing due to lack of knowledge of how to treat vitamin deficiency. I do not have a solution I just know no one else does and many make the error of under supplementing and simply waitig because that works or is acceptable to some. I have studied the methods of establishing RDA's and expect it is not scientifically sound. It was developed after WWII when science was going to be the answer to all problems. That understanding still is prevalent despite the failed results.

So I would simply increase to 4 times a day but I had scheduled my next trial to be magnesium. For many reasons none of them connected to following or hoping I can magically find what works best that is likely the best course of action.

I took B1 and B6 orally a couple of hours ago and can expect that I will be on enough to do the research I want to do to determine what form of magnesium has the most likely efficacy for me and at what dose to start. I am an active 180 pound male.

[mickeymouse42]

As you say, the B1 blood test doesn't appear to be accurate. The companies that sell blood tests say that it's accurate but the Mayo clinic says it's not: mayocliniclabs.com/test-cat...

Leaving aside B12, which blood or urine tests are accurate when testing the B family? It appears that niacin (B3) for example can be tested accurately via blood and urine tests.

The reason I ask is that though I don't have PA, I've had an ileocolonic resection and have bile acid malabsorption (BAM). I've had Vit D deficiency and very low B12 which I correct through high dosage supplements. It's hard to know whether it's the ileocolonic resection or the BAM that's causing the deficiency. In the case of Vit D it appears that BAM affects the CYP enzymes needed in the formation of Vit D.

BAM research is very active (it apparently affects 1 on 100 people) but there's not much research on how it affects absorption of Vitamins and gastroenterologists don't seem very interested in the issue; Professor Spector is a notable exception but the ZOE project is not currently looking at gut diseases or malabsorption issues.

[posthinking01]

Not sure if this helps but a few years back I used to get regular testing of numerous vitamins and minerals and hormones - every 3 months - I would be given the supplements etc. that the test were showing were deficient and then three months down the line those would be ok via the blood test or urine test in some instances but now there were others that had gone out of balance. I do know that if the body is very deficient it will 'grab' what it needs to keep the body going - I had an instance with COQ10 when I was taking thyroid hormone that was too high a dose and COQ10 is something that the body needs for the heart muscle and my levels went up to over 7000 when I wasn't even taking it - so I am convinced my body was trying to help me with a heart muscle issue - I have also experienced this with vitamin C too.

[WIZARD6787 in reply to posthinking01]

It makes sense to me that the human body can adjust very well to many different diets and therefore nutrition.