I've got some Cytoplan B12 which says it's 500ug of methylcobalamin and 500ug of adenosylcobalamin.
Does anyone know if this is as effective as 100% methylcobalamin? It's certainly a better price but not if it's not as effective!
Any info please. Thanks.
It should be equally as effective as 100% methylcobalamin, which should be equally as effective as 100% cyanocobalamin and equally as 100% hydroxocobalamin.
Once they enter the cell all forms of B12 are immediately converted to cob(II)alamin. From that point on they are indistinguishable. b12science.com/B12Science/D...
Where did you get it from ?
I bought this just to compare it to other brand and I feel cytoplan is ok. But eventually I will go back to cyanocobalamin because of it's stability and price. At least I have understood cyanocobalamin is the safest bet that way, you know what you get.
I thought cyanocobalamin had to be converted to methylcobalamin before your body could use it, and that's why methylocobalamin is the best to take - maybe I've understood things wrongly? I thought some people have a problem converting it.
Nope. the 'people have problems converting cyanocobalamin to methylcobalamin' falsehood is part of the magic methyl myth, spread by people who make money from selling supplements, books, speaking tours and adverts on clickbait websites.
All forms of B12, cyanocobalamin, methylcobalamin, hydroxocobalamin and adenosylcobalamin are converted to cob(II)alamin as soon as they enter the cell. From that point onwards they are indistinguishable. b12science.com/B12Science/D...
Can't say for sure, maybe it's more about the stability as all other forms are more fragile/harder to make. Maybe it's all about inconsistent potency when it comes down to other forms than cyanocobalamin.
On the other hand there is study about one type of MS that is destroying a protein in cycle where adenosylcobalamin is formed so there it would about not being able to convert other forms to adenosylcobalamin and when injected adenosylcobalamin it fixes the issue and all symptoms disappear.
So yes there could be flaws in converting different forms but how common is that, that's another question.
I do very well on cyanocobalamin, but also that cytoplan methyl/adenosyl seemed to do good instead of just methylocobalamin. And I happen to have MS.
sciencedirect.com/science/a...
Link to the study of adenosylcobalamin and MS.
For some reason nobody is quoting that paper in later work. There is only one paper that cites this one, and it's in russian so I don't know what it's about.
It may be that there is an obvious fault with the study described. The author claims amazing results with adenosylcobalamin but doesn't seem to have tried any other form of B12. Indeed, it's entirely possible that many of his symptoms were caused by a B12 deficiency as he doesn't mention if he was tested. B12 deficiencies, it seems, are not unusual in those diagnosed with MS.
Sure it all could have started just by simple B12 deficiency.
But co-existence of these conditions STILL seem to be hebrew for some neurologists. I am not followed nor supported B12wise by my neurologist. They did not test me further when I told I am on B12 injections , they just wanted to diagnose MS and push medication when I did not even have any active lesions, I just had had optic neuritis.
No interest whatsoever even though I said my symptoms disappear on injections. For me symptoms were fatigue and lack of stamina/lactic acid type of build up/ food not turning into energy pointing out something wrong in Krebs cycle.
Point was that it could be possible there are real reasons why one need certain type of B12 but maybe not as common as thought and the rest is just about finding supplement that indeed equals cyanocobalamin in potency and administration of it is corretc.
Sounds great. Where can I buy it? I’m in US
If you mean the Cytoplan see above 
As I said last week Cytoplan seems ok but have to add it seems more than ok. I have had issues with rapid heartbeat especially in the morning and none of other supplements seem to do the trick but now three days on the row heart rate settled.
I don't know what it is but just methylocobalamin won't work nor worked cyanocobalamin which actually was the least effective orally (injectable cyanocobalamin does work for me).
But Cytoplan methyl/adenosyl seem to be most effective for me atm. Don't know is it about the form of B12 or just the product itself being quality product.
And I have had rapid heartbeat especially in the mornings since my last injection wore out so about 5 weeks now. So either it's very sweet coincident or it really works and my rapid heartbeat was about needing B12.
Hydroxocobalamin or Methycobal (Mecobalamin) for self-injections?
Anyone tried the B12 nasal spray?
Is Anyone Self Injecting Methylcobalamin?
Depression after sublingual B12
