Vitamin B12 methycobalamin brand

[Thulasi1]

Hi All,

I am diagnosed with PA and started taking methycobalamin 500 mcg every other day from 2 months in India. Some symptoms reduced. I tried hydroxocobalamin 6, 1000 mcg from Rotexmedica as I am in Germany now. Seems like Hydroxocobalamin is not working ( I experienced this in India so I carried some 1000 mcg methycobalamin ampoules from different manufacturer than 500 mcg methycobalamin ) I already injected 6 1000 mcg methycobalamin injections every other day and they don’t seems to work either. All of the initial symptoms are returning back very hard. I am not sure why it’s happening. The only option now available is to travel back to India and get 500 mcg methycobalamin from the manufacturer I took for 2 months that worked well. Please advice if I have to wait for few more days with few more injections. I am totally down with same neurological symptoms not able to sleep as the nerve tingles, pins, needles, buzzing in ears, breathlessness and vibrations like an old person when I still 30 years.

[pvanderaa]

Are you supplementing with folic acid and a daily multivitamin to help B12 do its job?

I’ve found methyl, hydroxo and cyano all work about the same and last about a week for me.

For folic acid, don’t take more than 5 mg daily. Take what you can manage.

Once you start on injections, new symptoms can show up that are very similar to your symptoms from the deficiency. It is counterintuitive and very confusing.

The symptoms like pain in the first three days after each injection can be from nerve repair sending stronger signals to the brain. It takes the brain about 3 days to recalibrate to the stronger signals.

I would stick with hydroxo for now and hold your methyl in reserve. Start gentle range of motion exercises to move the muscles in order to stimulate nerve repair as well as recalibration for the brain. The hardest part is getting started. Swimming is a good all around exercise.

Your panic and anxiety are a psychological symptom brought on by neurological damage. If you can measure it, treat it like any other symptom.

Do you keep a logbook of your symptoms?

[Thulasi1 in reply to pvanderaa]

Hi pvanderra,

I have already gone through initial roller coaster with loading doses of b12 injections every alternate day for two months. I am not sure why only particular 500 mcg methycobalamin from one manufacturer works very well. When ever I try hydroxocobalamin or methycobalamin of other manufacturer all the symptoms return back and I try continuous 6 injections of them with no use. Once I return to 500 mcg methycobalamin of the said manufacturer the symptoms again comes down. I am not sure why this is happening and is strange to me.

[Thulasi1 in reply to Thulasi1]

Yes I do take multivitamin and 700 mcg Folic Acid is Part of the methycobalamin injection + 200 mcg Folic Acid from multivitamin. My serum folate level is on the upper limit of the range so I am little worried of more Folic acid.

[noszbe in reply to Thulasi1]

I wrote this in response to someone else, but it might apply to you:

If you are using "folic acid" rather than "methylfolate", then that could be messing with how the B12 works. In some people, it makes a big difference, e.g. pnas.org/content/106/36/154... and probably explains the much higher rates of certain cancers associated with folic acid, and lower rates with methylfolate e.g. ncbi.nlm.nih.gov/pmc/articl... . The high level of folate may be masking high unmetabolized folic acid (UMFA), e.g. ncbi.nlm.nih.gov/pmc/articl... sci-hub.tw/10.1007/s10815-0... etc

[Thulasi1 in reply to noszbe]

Thanks noszbe for info. I will stop taking Folic Acid and Start methylfolate if needed. There are quite some people taking 5 mg Folic Acid and May be they can have a look on this.

[Catman1]

Maybe worth trying the 5mg (5000 mcg) methylcobalamin ampoules. Easy to get here but very expensive unfortunately.

[IMINHIM]

any medications-----how about your b12 tests----and how about vit d3 levels and magnesium levels----low magnesium can masks some of the b12 symptoms----how long have you been taking the b12 shots----I would like to follow your posts-----be blessed in your journey magnesium is responsible for hundreds of enzymatic functions in the body----im not a dr. these are my opinions-----but it is from info I have picked up from knowledgable people-----startingmy own journey good luck

[Dvpk24]

Hello. I am from India as well. Can I contact you for more information. I am going through this from 2 years.

[Thulasi1 in reply to Dvpk24]

Hi DVpk24, sure