Liposomal B12, a great idea?

[whitenoise]

Hi everyone. Has anyone considered using Liposomal B12? I don't see much (if any) talk about this anywhere, and I'm thinking that this could be a great product to use instead of (or for those who can't get) injections.

Without going into too much of my history, I've been a bit fan of Vitamin C for the last couple of years after being diagnosed with testicular cancer. After surgery, refusing chemo, I started to read every book on the subject I could. Now I'm a big fan, and especially of Liposomal C. If you are not sure how liposomal products work, they are basically made out of the same material as a cell membrane. Liposomes can be used to deliver ingredients and actives to the cells where they will be used. You can google it for more info.

Now strangely I come back to B12 after intially looking into this years ago. This lead me have my 9 mercury fillings replaced, along with removing 3 root canals. B12 problems are in the family, so I don't know why I didn't really go into that much, but I've come back to the subject and investigating further.

I've ordered the B12+ tests from Viapath (Total + Active B12, MMA, Hcy + Folate), which is very good value, and also IF antibodies test.

Now, after my success with lipoC, I noticed the same company selling lipo B12 (I don't sell or have any connection with this company by the way). This seems like a great idea, since thats why people have injections because B12 can't be absorbed. So if you combine some B12 into a liposome, this bypassing digestion and can get straight into the blood and cells?

Now I don't see much about this, so perhaps there is something I'm missing, as to why more people aren't using this?

[fbirder]

Smells like snake oil to me.

How are liposomes supposed to get that huge B12 molecule into the bloodstream?

[whitenoise in reply to fbirder]

There is a lot of information out there on liposomes and how they work. The technology and process doesn't change, just whatever you put inside the liposome.

1000mg of Vitamin C is contained inside a 200 nm liposome apparently, so can't really see how putting 1000mcg (which is what is used) could cause an issue? It comes in a pipette and 1ml contains the amount above in the Hydroxocobalamin form. Just put in a small glass of water or something.

After I've done my tests I going to give it a try and see how it goes.

[fbirder in reply to whitenoise]

It’s the size of the individual molecules that makes a difference. Vitamin B12 is about 7.7 times larger than vitamin C.

It the hydrophilic nature of B12, plus its large size that makes it hard to cross membranes like those of the gut. Using a liposome as a carrier might help with the first of those.

I’ve not been able to find any scientific studies on liposomal delivery of B12.