I have been scrapping at the bottom of the range 196 [175-190] for years and so I self-prescribed 1000mcg cyanocobalamin as my GP wouldn't help and just chirped "you 're in range". This took the value up to 380ish. I stopped taking cyanocobalamin as I have gut dysbiosis/damage and didn't feel it was being absorbed efficiently. I am on a mega SIBO dietary/treatment protocol now and popping supplements including HCL/Pepsin/ACV with mother for my hypoclorhydria.
As I have Hashimotos thyroiditis and need to be in the top quarter of the range I decided to start taking 5000mcg Jarrows Methylcobalamin sublingual about 4 months ago (and Jarrows Vitamin B Complex) and my last two Serum Vitamin B12 results were 439 and 398.
My plasma homocysteine is 4.4 umol/L [<12] so I have been told by my nutritional therapist that my methylation pathway is OK ??? Does that mean I should be able to metabolise the methylcobalamin?
Is hydroxy/adenosyl better?
Does anyone have any suggestions about what to do to get to the top quarter of the range and where I can source a 5000mcg Vitamin B12 please? I take 42 supplements per day and really don't want to be taking 1000mcg x5 tablets if I can help it
Thank you everyone