Carboplatin and liposomal doxorubicin

[Gonewith]

I had a ct scan three weeks after my CA125 keep increasing last six month as soon as finshed 18th IV of Avastin.

Upset and nurvouse not knowing what will be the side effect of this 2nd line of chemo starting on 27th Dec.

Can anyone please share what side effects did they have, having these two drugs (Carboplatin and liposomal doxorubicin).

Many thanks x

[DianaPrince_]

I've just finished 6 x Carbo + Caelyx (liposomal doxorubicin).

I found it doable.

I had it every 4 weeks. And the first 10 days I was very fatigue and mostly slept and sweated through it.

I got a few more migraines than normal - I do get them anyway.

I couple of nasty rashes that i needed meds for.

A smattering of diarrhoea and constipation. And learned to never trust a fart when on chemo.

Nausea meds were very much needed.

So was meds for acid reflux.

Didn't lose my hair but it did thin a little.

Was less painful than on Carbo + taxol. which made my joints and bones ache.

Hope that helps.

[Gonewith in reply to DianaPrince_]

Thank you so much for your message. I was so desperate to hear from someone how they gone through it.

May I ask if you will be on any maintenace? How was effetive on your CA125?

Best wishes xx

[DianaPrince_ in reply to Gonewith]

For maintenance i'll be on Avastin (IV).

Ca125 was 200 when recurrence could be see on scans.

And is now 10.

Got to 10 by 4th chemo.

CA125 is a very sensitive marker for me.

I'm BRCA 1 so very sensitive to platinum chemo.

[Hockeymom52]

I’m on it now. I find it much easier than carbo/taxol. I feel very fatigued the first 3 or 4 days after and slight nausea. I get it every 4 weeks so which makes it very tolerable. I have a little bit of skin rash on my arms that is not itchy I believe it’s from dry skin so I use CeraVe which helps.

[Gonewith in reply to Hockeymom52]

Thank you so much for you message. How about your hair? I just cant think I can go through losing it after a year again

[Hockeymom52 in reply to Gonewith]

Did not lose my hair just a little bit thinner. I was afraid of losing my hair again too but my oncologist told me that it might just get thinner. So far so good!

[Gonewith in reply to Hockeymom52]

Thats good.

Wish you all the best xx

[Hockeymom52 in reply to Gonewith]

Wish you the best as well! Happy Holidays! xx

[Towergirl]

I had 6 cycles this year of Carbo & Caelyx. It was every 4 weeks and doable.

I did lose my hair, not totally but very patchy. I have fine hair, showing scalp and ended up having to cover. I was told I wouldn’t lose hair again and didn’t use cold cap.

Needed plenty of moisturiser as skin got very dry.

Chemo did drop my platelets and coursed delay of last few treatments.

Best wishes xx

[Gonewith]

thank you so much for you reply.

I suppose we are all different and react towards these drugs differently. So sorry you lost your hair again. My plan is to use the cool cab as I heared helps the growth even not stop the losing.

hope you are doing OK now.

Best wishes and regards xx