Second Reaccurrence

[BadgerBright]

I have been in the maintenance drug rucaparib since March 2022. After some dose reductions I settled down to it quite well apart from from blood transfusions due to low haemoglobin. However, at my last CT scan this June my lymph nodes had swollen suggesting the rucaparib was no longer working. I was very disappointed at this news but knew I had to accept the facts. So in Aug I am back on 6 sessions of Carbo chemo. I have already had two lots of 6 cycles in 2020 and 2021. This feels like quite a journey and wondered if any one else has had these experiences?

[Fizzgirl]

Hi BadgerBright my story is similar to yours. Diagnosed Jan 2018 had surgery and chemo, first recurrence Jan 2022 had carbo and taxon. Then went onto Rubraca as was told there are less side effects. I had dose reductions too as my haemoglobin was very low and had four blood transfusions. At 10 months had CT scan and it showed progression so Rubraca was stopped and now on carbo/ caelyx. This time neutrophils affected and even though chemo is every four weeks it keeps being delayed due to my blood results. However CA125 is down into normal range. I hope you get on OK after chemo it's watch and wait for me xxx

[BadgerBright in reply to Fizzgirl]

Thanks for your kind message Fizzgirl. Do hope you continue to get on with Carbo/caelyx despite delays. Good news 125 is back in the normal range. We must grasp the positives and keep on going. xxx

[Leniko in reply to Fizzgirl]

yes, and it is frustrating. I’m on my 4th recurrence. Various chemo’s and radiation have worked for a time. Recently, my maint Avastin has stopped working, so I will have more radiation for an OVCA tumor on my psoas muscle. I will keep doing whatever needs to be done. As long as I have quality of life, I will fight!

[BadgerBright in reply to Leniko]

Sorry to hear about your 4th recurrence Leniko and what you have been going through. You are completely right as long as you have quality life you have to keep on fighting. Thinking of you through it. Many Thanks for the inspiration. BB. xx

[Casamimosa]

Hi, I was on maintenace olaparib for just over 2 years and did well on it. after 6 chemos/ op / then 3 more chemo and was feeling really good the ca125 started creeping and like you lymph nodes problem. So have just finished my 4th round I'd carbo taxol 2 more to go. I have had different after effects from previously that I put down to being much stronger than last time. I have suffered mild neuropathy. But I have found hot water bottles by my feet at night helps/ Epsom baths or foot soaks/ I have taken ibrobrufen & paracetamol when really bad but this last time not had to. Drinking lots of water and fluids and gentle walks keep circulation moving. I have around a week of not being great but try to power through a bit. Hope this helps. Good luck. We can do this !!!

[BadgerBright in reply to Casamimosa]

Hi Thank you for your very helpful and very inspiring message and really useful tips and information which I will remember when I start my chemo next month. Interesting that your side effects have been different, good you have found ways to ride them out. Hope the last two rounds continue to go well. Much good luck yourself going forward as we can certainly do this.!!! Thank you again.

[Casamimosa]

Ps my car 125 now down to 51 from 174 so positive results so far .

[BadgerBright in reply to Casamimosa]

Forgot to say in my last message. This is really great positive news.

[Casamimosa]

Yes. I am very hopeful that this round will keep it at bay for a long time. Yes I was surprised that my after effects have been different but I was extremely poorly first time round awful sickness etc and told at stage 4, as I said this time I didnt even feel anything was wrong but the bloods showed otherwise 😅 good luck and let me know how you get on. Ps make sure they give you antisickness pills etc sure these have helped.

[BadgerBright in reply to Casamimosa]

Thanks for the info on antisickness pills. I have also found real ginger sweets helpful in the past. I will let you know how I get on. You let me know also how you get on. BB.

[Casamimosa]

Still here over 3 years on.

[BadgerBright in reply to Casamimosa]

Brilliant news.