Dear all,
I have been reading all your posts for a while and appreciating all the support and information you share in this wonderful community. Today I decided to post for the first time about our situation:
My mum (56 years old) was diagnosed in May 2018 of low grade OC, stage 3C, while on surgery to remove ovaries after finding a mass in the ovary and CA-125 levels of 188. They found a huge peritoneal carcinomatosis that was also extended to the surface of intestines, liver and diaphragm, and concluded it was not operable. She had 3 cycles of neoadjuvant Carboplatin-paclitaxel-bevacizumab and after that the CT scan showed a mild response (did not expected more as she is low grade...) and also a reduction of CA-125 levels to 78. Then she was scheduled for an exploratory laparoscopy to see deeply inside the abdominal cavity and evaluate if she was now candidate for debulking surgery and HIPEC. However, the omental cake is so thick that surgeons could not even enter, so we have just been told it is still not operable. Most probably will receive 3 or 4 more rounds of chemo and re-evaluate, fortunately at least she handles it really well, with almost no side effects. But as chemo has not done much until now, I really do not expect a huge improvement... Any experiences with low-grade second line therapies? I have read about hormonal therapy and we are still waiting for the results of BRCA tests. Any advice will be very much appreciated.
Thank you all for your kindness and support!
Sara.