Low grade serous carcinoma

Another concern is she is pretty young, she is only 27. I hope she recovers soon. Going through very tough time and I need the community to share their experience.

Hello,

Hugs on what you and your wife are going through.

In early 2016 I was diagnosed with low grade serous cancer. In my case, it invaded the bowel. I had a bowel resection (lost 8" of the colon), and like your wife, the cancer had gone into lymph nodes.

I was told that low grade serous was a slow moving cancer.

In my case, chemo wasn't horrible. I had fatigue and neuropathy, but in hindsight, that was all an acceptable trade-off for still being alive today. Your wife is strong and young. That will help her.

It sounds as if you are a supportive husband and you need to remember to take care of yourself.

XXOO

Hi

I was 47 when I went through what your wife is going through/about to go through but I can assure you that the chemo is totally doable. Once bit of advice I always give is stay off google. It will give you all sorts of statistics (mostly outdated). Your wife isn't a statistic she is unique. Google cant tell you what will happen but it will scare you unnecessarily. Yes your wife will have side effects from the chemo but she will have access to a team who will look after her. Tell her not to suffer unnecessarily. If she has nausea or any other symptoms then to let her CNS know so that they can give her the right meds. Not all antisickness work for everyone and sometimes need to be changed. The fact your wife is young and strong is on her side. Make sure you get any help YOU need too. This journey will affect you too. xx Big hugs to you both. Kathy xx

Hi. Im sorry you've found yourself in this situation. This is a fab site with lots of support and very helpful advice. You will notice many women here are a bit older, as it is more common in that age group, but there are a few of us a similar age to your wife (I'm 33). My oncologist told me that younger women tend to do better as generally we have fewer complications.

I agree with the advice you've already received- stay off Google! Can I ask how you were told the stage without your wife present? My husband tried to speak to my surgeon without me present (I was knocked out on morphine) and he wouldn't deliver any news until I was awake.

It is a rubbish place to be but there are some exciting trials in progress and there is absolutely no reason why any one of us can't be a survivor 😊

Wishing you all the best through this.

Hi. I had surgery last dec and finished my 6 chemo cycles 2 mos. ago. Chemo wasnt that hard for me except for weakness 5days after each cycle (each cycle is 3wks) and neuropathy. I didnt experience nausea and pain which was good for me. But now I have some joint pains and lose bowel which Im hoping is not a serious matter. I'll have a PET CT scan next week and im hoping it will show NED☺

Your wife is young and so is your kid. She's more inspired to win this battle so believe in winning! And most importantly, pray a lot☺ God bless!

Why aren't you telling your wife everything?

I would be very upset that someone I loved wasn't completely honest with me. I hope she will forgive you.

So sorry about your wife. My mom is also battling the same cancer, was diagnosed 2016 and surgery 2017. They need a whole lot of our support. Just keep the faith and lots of prayers🙏🏼❤️

Hi prateek0490

I’m glad you found this site as it sounds like you are taking on a lot and you need to share and get support. Our partners are often forgotten about when we are going through this and they give us so much support but you need to look after yourself too. Do you have family and friends around you. Please do talk to them. They can do so much for you. Dinners are a great help as chemo effects everyone differently but fatigue is the most common and if there’s one thing you don’t need to think of then you can spend time with your little boy and your wife. Take all the help you are offered. There was a team of ladies from my kids school dropping in dinners and although it might not of always been something we liked it was much appreciated when I was lying on couch with no energy and hubby didn’t have to come in from work and start cooking.

When I was first diagnosed with stage 3 i didn’t think Of the number as my surgeon said stage 3 but curable. I did 3 cycles then surgery radical debulking hysterectomy and a bowel resection. It was also on my liver but chemo had removed Most of it and he got the rest. He was confident he got everything. After another 4 cycles of chemo there was no reoccurrence and no residual. That was last June 17. I have just finished another 6 cycles yesterday from a reoccurrence in Jan of this year but scans show NED and tumour markers are down to normal. So medicine is fantastic now and always improving. Ask oncologist lots of questions and just take a day at a time. And as some of the other have said the bowels are key. Not getting constipated is so important and the medication does this. I avoid the anti nausea ones if I can..not always possible. And I avoid wheat as only read recently from another patient that wheat is like cement in your bowel when on chemo. Lots of water fluids prune juice all good.

Lastly counselling for your wife and also yourself maybe. Very important to be able to vent and get it all out. And we are all here for you too. She will get through this. You both will. Take care and please do get the support network around you. Antoinette.

Hi I’m low grade diagnosed last year 3c at 42.

They tried chemo but it did not work and This is the case for some low graders as the cancer is slow growing but not all it works for some.

I’ve learnt we are all different

I’m on hormones now and in remission

Thinking of ur wife.

Hi there

I too have stage 3 low grade, spread to lymph nodes. I had surgery last May, did chemo and am now on hormone anhibitors as low grade is generally a hormone driven cancer. Lots of research from MD Anderson in the States on the benifits of hormone inhibitors after chemo to delay reoccurrence. It’s just a daily pill, mine is called Letrozole. Very easy to take. MD Anderson is the hospital that specializes in low grade. I do believe there is also a doctor in Edinburgh who is also specializing and very knowledable.

I was told stage 3 is not curable but manageable, like diabetes for example. I feel great a year later. Back to work, travelling, life is good. Chemo was hard first round and there is so much anti nausea meds out there. Day 2 and 3 are generally rough and by end of second week you feel your strength is back.

Low grade is slow moving and often see as chemo resistant as chemo attacks fast growing cells. However it is the standard of care that is recommended. Went to a presentation yesterday from top reasearchers In clinical trials who said that some trials will disqualify you if you don’t have a session of chemo first. ( if that’s what’s your looking into later down the line)

Many new treatments are on the horizon right now , targeted therapies, immunitherapies. Things are starting to move and I feel positive.

I wish you and your wife every strengthAnd comfort. Please feel free to message any time. There’s not as many low graders out there as high raiders so we need all the support we can get. Facebook has some good low grade groups.

I have 3c low grade oc. Has radical hysterectomy Jan. 23 3018 and started chemo Feb 27 and finished July 3rd. Really had no side effects except my hair. Had hair down to my butt.😏 had a few visits from gastritis and bowel obstruction caused from surgery. Try to eat lots of fruits and vegetables. Pain pills and pills for nausea will constipated you. Also take stool stoftners and laxative. Some ins. May cover it. Mine did. When really bad take maralax also. I was lucky did not have to take pain or nausea pills.good luck.

Hi there. I have stage 3 Low grade Serous Carcinoma. Low Grade is slow-growing and oncologists say it's completely different from High Grade, so only look at Low Grade articles if you look on-line. Your wife is young and that's in her favour as she will be strong physically. Lymph node involvement may not mean a worse prognosis for Low Grade. It often just sits there and doesn't do anything. Maybe they got all the affected nodes? The chemo is standard for all of us. You may want to find out if the tumour is Estrogen Receptor positive as she may be able to take aromatase inhibitors such as Letrozole later on. Some oncologists now use them instead of chemo first, but the national guidelines still recommend chemo first. I think she'll do well with chemo. Younger ladies don't mind it as much. Take care of yourself too during this time.

Hello! I too was diagnosed with Low Grade Serous - at stage 3c. Mine was spread throughout my abdoment and I was experience a lot of ascites. I had to have neo-adjavant chemo before I was a candidate for surgery. I had 2 rounds, then surgery, and then I had 6 cycles of IP chemo - which was very hard and I have lasting neoropathy from. However, the great news is that i have celebrated 3 years since my diagnosis and I am in remission and very strong. My advice is to fight as aggressively as possible. However, research shows that LGSC is chemo resistent - but slow growing. what is CA125?

Hi I was diagnosed last november with stage 4 ppc at age 35 I was admitted to A&E with a plural effusion had it drained I couldn't have surgery as it had spread so had 6 sessions of carbo/taxol with avastin and had partial response, try to organise who can support you during treatment or even offers of help with meals housework is very helpful. I had about 4 sick days a month and you would be tired but we had lots of good days in between and booked a holiday after it, I am on avastin my cancer didn't go away but its suppose to control it, I am 3 months out of chemo, Complementary therapies were very useful to me I did reflexology and mindfulness and then I started yoga, reiki and nutritional therapy after it. Message me any time if you want to ask anything about coping with treatment side effects, hairloss, make-up anything its all so hard at the start but it quickly becomes the new normal and try to be as positive as possible. xx Take care

Hi Prateek. Mine is a low grade / borderline stage 3a tumour, which recurred much faster than expected, after two years.

I understand you don't want to cause your wife too much worry. The fact that she is young is, while tragic on one hand in terms of more children, probably a positive factor where the cancer is concerned. Hopefully it will stay away for good or at least for a long time.

But: Stage / spread of the tumours impacts recurrence risk. It may return. Don't you think your wife might want to make different life choices based on that knowledge? E. g. travel more now rather than in 20 years, eat differently, etc.

I would tell her, because it is her body, her life, her truth.

All the best to her and yourself. Maus.

Hi Prateek, which country are you located in? In most countries, the patient must be told directly and, of course, has to be present. Imagine if the situation was reversed and she wasn't telling you the full truth about a serious medical condition you had, and its possible consequences. How do you think you'd feel?

Hi there I am a fellow low grader.. Diagnosed in the ER on November 20th 2017 I have 1 more chemo left . my most recent CA-125 was 99 I will get it re drawn on Tuesday the 31st while at my last chemo. I have a CTscan on August 8th and I am hoping for good news. This is all so very scary but there are more and more success stories. Please do not read the statistics on google they are all very old! Feel free to reach out at any time... Best of luck...

Thank you everyone for your well wishes and support She knows what stage it is and have also consulted our dr team for the same where dr have told her that it’s curable and she will be alright.

But it wasn’t a good experience yesterday. Chemo has started, it was pretty tough the first chemo, her body wasn’t responding properly, it was Paclistar 115 Mg and

Carboplatin 200 Mg Injection.

She fell unconscious couple of times during chemo and was kept under observation for 12 hours. She is stable now and we’re done with first dose. Hope her body responds well in next dose and more doses to come.

Keep your blessings coming our way, we need it. Thanks everyone 🙏🏻