If I can't get on the trial I want to join, I may be offered these drugs. Is it right that they help to keep the situation in the same place rather than reduce the the tumours? Has anyone seen a significant reduction in disease using hormone treatment for PPC or Ovarian, particularly low grade. it'll also be good to know treatment outcomes from hormones for any grade. I want to say to my oncologist, well this MEK trial may be a better option since chemo isn't likely to work. T x x