Hi I put a post on the other day about comments on Tocilizimubab as I hope to start in the next few weeks .. in the meantime Friday I had a steroid injection as I’m in so much pain but I’ve had no relief . It was a depo medrone in the bottom , has anyone else had a failed steroid injection or is it still too early for me to presume , just so disappointed as I’m really struggling , signed off work etc .
Thank you
I’ve had one; thought it was a complete waste of time.... until 3 or so days later when it kicked in. It then did great for quite a few months.
However we all react differently; but fingers crossed
Hi,
Back 6 months ago i had Depo Steroid injection in Pain Management Surgery.
I had 1 i n back of each shoulder and 1 each side of my lower Spine. all at the same time.
But I was so disappointed, because they didn't help me at all.
The thing is you'll try anything when you're in pain .😭
Sorry to say I’ve had two general Depo-Medrone injections. I had no relief from one but the other I had one whole day of wonderful RD-less symptoms around a week after it being given. I've mentioned it here before & someone suggested I asked for Kenalog (triamcinolone acetonide) if I was offered a general again, possibly you could too? Worth the ask. Oddly, I respond well to targeted (local) Depo injections.
Obviously I hope this one works for you but if not & you're still in pain do report it to your team so they're aware otherwise they'll think all is well.
Thank you yes I will definitely mention .
I'm the same. Kennalog into the joints work well for me whereas general depo injections are very hit and miss. Mine seem to depend on which nurse gives them and how careful they are to find the correct spot
Yes I’m afraid I had one injection last 2 weeks then had another I got no relief at all 🥺🥺
It’s so disappointing isn’t it 😢
Same here I had the same steroid injection twice and nothing. you are right it is so disappointing.
I had a depo Medrone when first diagnosed but unfortunately it did not give me any relief. I do hope it works for you. A ultrasound guided steroid jab ( into finger) worked a treat at a later date for that particular finger. Don’t suffer on and speak to your Rheumatologist about another course of action.
Yeah that sounds like my experience. It did absolutely nothing for me when I had one a year ago.
It seems there is no rhyme nor reason....to knowing if Depomedrone will suit you, I’d had Depo jabs for years very successfully....I got 10/12 weeks relief.
But this year I had one which made me really ill....I had to cancel a holiday....& it took a good two months to get back to normal.
Two Rheumatologists “thought” the anaesthetic used might have caused the reaction....but said it was unlikely.
I just hope I don’t need to make the decision whether have one again,
I find if i have it into the hip it does not work for me but if they do it into the joint it works much better. Hope it works for you
I've had three injections. The first one did nothing at all. But the second one was great - I felt so much better for about three months. Then the third one had absolutely no effect. I was so disappointed because I was really struggling. The rheumatologist said there was no point in trying another one and prescribed steroid tablets instead while I was waiting to start Tocilizumab, so maybe that might be an option for you?
On the plus side, the Toc has been reasonably effective. I can't say my symptoms have all vanished but I'm much more mobile than I was and in a lot less pain so I hope it works for you too.
Keep your chin up and best wishes!
Terry
Ive had a few kenalog injections and they've always worked for me but when I had two consecutive ones before tocilizumab kicked in the second one wasn't as effective. On the plus side tocilizumab has been amazing
Thank you that’s so good to hear , hopefully they can get the the Toc nurse , prescriptions etc sorted soon ..
I also had no relief from a steroid injection in my bottom. Hard to understand why because other ones have been effective. So I had oral prednisone until I started humira.
I've had a few since being diagnosed with RA 7 years ago. A couple of depo injections didn't work, presumably because my symptoms were so bad (knees like melons, fingers like sausages, excruciating pain almost everywhere). I just had to wait to be given the biologic. Other depo injections have only worked when my symptoms were not as bad. Had last depo in spring this year so could enjoy a holiday and the nurse told me to take things easy for a week after the depo. This was to let my joints adjust.
I have had several general steroid injections & they have been so different. Some have been wonderful & have worked very quickly, some just helped slightly but the last two have not helped at all which has been very disappointing. I have wondered if your body gets used to them after a time & they stop working but that wouldn’t be the case with you. Perhaps the dose wasn’t strong enough.
I think your body may get used to them too as I’ve had them in the past and it’s been like magic ...
My physio says to get maximum effect, you have to go straight home and lie in bed for 24 hours. It's not always possible but I try.
That’s interesting.. thank you 😊
I have been told to rest for 2 days after an injection but not to lie in bed like that. I wish they would all tell you the same as it gets very confusing to be given different advise
I had a steroid injection when in a mega flare but it didn't have any effect, no relief at all. The nurse said that they don't work for some people but nobody knows why. Good wishes
sorry Claireyj to hear you are having such a rough time. I have had steriod injections in the past and they have worked within 3-5 days. However, this time, on both occassions it hasn't worked, infact the last one just spurted right out. I guess it is a hit or miss, I truly hope it kicks in soon, fingers and toes crossed.
I've had 2 depo medrone injections with no effect.
Oral prednisolone does the trick for me. Like others have said I would let your rheumatology team know it is not working for you.
Steroid injection
Steroid injection 
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Steroid injection 
Steroid injection 
