Higher dose of Methotrexate

[Littleredrobin]

Hi there, Last month I had my methotrexate dose upped from15mg to 20mg which I inject weekly. It does seem to have helped in settling the pain down but I am feeling quite nauseous and also getting stomach cramps. I just wondered if this is likely to settle down as my body gets used to it or is it that I am going to have to choose between the pain or the nausea?! 😌

[AgedCrone]

Are you taking Folic Acid? That calmed down any nausea for me, plus keeping well hydrated....in the winter I started drinking hot fruit teas rather than gallons of cold drinks.

Hope it settles soon.

[Littleredrobin in reply to AgedCrone]

I have only just this week started taking Folic Acid so hopefully that will help and thanks for the tip of keeping well hydrated - I always mean to but have a habit of forgetting!

[AgedCrone in reply to Littleredrobin]

I think we all MEAN to drink more.....

Little tip...make up a jug of your favourite juice,quash whatever....And leave it on the kitchen surface where you can see it every time you go into your kitchen. It takes two seconds to drink a glass of whatever and every little helps!

I know ....really nerdy...but if it helps ...why not be a nerd?

[Hidden]

I too am on 20mg methotrexate injections. I’ve been on them 6 weeks. At first if I feel nauseous and wiped out . This week I’ve been fine. Hope this continues 🤞

[Littleredrobin in reply to Hidden]

I hope so too 🤞 and hopefully I may be the same 🤞

[Thingybob]

I've just upped my dose to 17.5 and get the travel sick feeling and lethargy the day after. I was advised to drink lots and eat carbs which seems to help. I also take folic acid 6 days , not mtx day. I inject in the evening as then hopefully sleep off the worst side effects overnight. I never plan anything much for the day after injecting just in case as side effects vary from week to week. Its a trade off between side effects and some relief for some of us i guess. Take care

[Littleredrobin in reply to Thingybob]

Thank you for the tips! And yes the nauseous is horrid but still better than the constant aches and pain 😌