I was diagnosed rheumatoid and February I couldn't get in to see a doctor until March. it is now April and I am on my third week of this medication. I have noticed a change in my digestive system. being the third week of treatment my stomach is upset and I also have headache and I have not slept all night due to this distribance. I feel nauseating when I think of eating..I now wonder should I go off treatment? Would my rheumatologist agree with me not wanting it? Wouldn't just predisone n nsids be enough to slow down my RA? I'm just upset and don't like feeling low key..All my activities has been put to a halt..because I can't move without pain or flare..I have been doing range of motions, but I don't know if it's worth the risk of taking this medication? ? Just confused? I know when I'm on predisone I feel much better n I know it's a on n off thing too. I'm 56 diabetes along with them wanting me to see a endocrinologist as well..all new diagnosis and I try to b positive. .I still have pain so is methotrexate worth it?