Second dose of Methotrexate...: Hi 👋 Hows everybody... - NRAS

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Second dose of Methotrexate...

regina79 profile image
24 Replies

Hi 👋 Hows everybody tonight? Finally Friday! It’s been a very long week for me.

Just took my second dose of Methotrexate. All 3 pills at once.. as I was instructed by my Rheumatologist. My mouth sores only just went away this afternoon but they might come back tomorrow.

Also had a painful horrible steroid injection in my shoulder earlier. Let’s hope that helps too!

My Consultant is away until September and I just wasn’t going to wait in so much pain in my shoulder and arm.

Wish me luck tomorrow with the side-effects and with a better shoulder and arm..

👌😎👋

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regina79
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24 Replies
JFlay profile image
JFlay

🤞🙏💪

regina79 profile image
regina79 in reply to JFlay

🙏😘

rab1874 profile image
rab1874

If things don’t improve maybe think about changing to injections, not as bad side effects I found I’m on 20mgs have been for 3 years

WomblingFree profile image
WomblingFree

I feel your pain. I’ve just switched from tablets to injections because I couldn’t shake all the side effects. I hope the steroid injection soon starts working for you x

regina79 profile image
regina79 in reply to WomblingFree

Thank you. But Do you still get fatigue even with the injecting or not? C

WomblingFree profile image
WomblingFree in reply to regina79

I had my first injection last Thursday and I’ve never been as tired as I was for 2 days afterwards. I had my second injection this Thursday and other than needing a bit more sleep, I was fine.

The tablets just gave me really bad diarrhoea but I’m not to bad now. I’m going out on a Saturday for the first time in 3 months!

regina79 profile image
regina79 in reply to WomblingFree

Sorry to hear your struggle with the pills. Glad the injections are better for you!

Have a lovely time out!! Xx

WomblingFree profile image
WomblingFree in reply to regina79

Thank you. I hope you’re feeling better soon x

charisma profile image
charisma

The injection might take a few hours or up to a week to kick in. I hope it works for you.

Mouth ulcers are one common side effect of MTX. I had one after my Amgevita injection two weeks ago as well. I hope yours heal up between doses each week.

May you have a much less painful weekend than in ages! :-)

regina79 profile image
regina79 in reply to charisma

Thanks so much! I wish so too. Shoulder and arm still tender but it takes time.

Not fatigue yet and it’s 10 am?! I wonder. But then I took Methotrexate quite late last night before bed. Last Sat I couldn’t move from My bed for hours. Fatigue might kick in later in the day 🤬XX

Nellp profile image
Nellp

Hopefully it will settle after a few weeks. I know it seems a long way ahead but most feel the benefits of being on methotrexate after 12wks. For example my feet felt like I was walking on stones and I was limited in distance to what i could achieve before it was unbearable. All that has gone and I cope with 3 to 4 miles albeit at a slow pace. My feet had been swollen but I had not noticed and after the 12wk period on methotrexate I dropped half a shoe size so once you start seeing the benefits it helps!

regina79 profile image
regina79 in reply to Nellp

Oh that’s fabulous! Such an amazing news for you! I can only imagine how happy you must feel at the mom. And I hope it lasts 👏🏻😊🙏x

Nellp profile image
Nellp in reply to regina79

It has lasted for nearly a year now. Just need to get the fatigue etc under control. I am sure you will start to see improvements.

regina79 profile image
regina79 in reply to Nellp

Amazing x

Nuttyshirlz profile image
Nuttyshirlz

I went up and down with all sorts of side affects when first started on mine. But my nurse said I had to give them 3 months and she was right lol now take them with hardly any affects.

regina79 profile image
regina79 in reply to Nuttyshirlz

Amazing! Happy to hear that xx

Nuttyshirlz profile image
Nuttyshirlz in reply to regina79

I was the same when I first started taking mine. X

Pulfs profile image
Pulfs

I changed from tabs to injection because tabs were making me feel sick. Only feel a bit fatigued, no mouth ulcers,for the next day no sick feeling now. As said can take up to 3mths to kick. Hope your pain not too unbearable take care xx

regina79 profile image
regina79 in reply to Pulfs

Sounds good Puffs! I’ll have to give it a go x

FunBalloon profile image
FunBalloon

I'm also on injections and I definitely have less nausea and tiredness the day after. Especially when you go up a dose it seems a bit better and effective than the tablets. So you might be able to be on a lower dose with injections than tablets. Most of my side effects did get better over time though. It probably took about 6-8 weeks I think :)

regina79 profile image
regina79 in reply to FunBalloon

Amazing thanks for sharing xx

I take my MTX on Friday too, I hope it works for you. I've had steroid injections in my shoulders, hip, knees and palm of my hand. I didn't feel too much pain, except for the one in my hand.

regina79 profile image
regina79 in reply to

My hands are really bad too lately :/ struggling to type and do other things.

My shoulder and arm feel better In the last couple of hours!!! I should have done it ages ago :/

NO side-effects from taking Methotrexate last night at all... yet ?! 😱 Not even fatigue. How weird. I feel like I haven’t taken anything. Maybe it will come tomorrow. Last week I felt weird and tired until Wed at least xx

embroy profile image
embroy

I had shoulder pain, as well, but the Injection made some difference, but have to keep up.with the exercises.

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