Have now been on MTX tablets 4 weeks and am now up on top dose 25mg. Took it last night and have felt absolutely dreadful today. Giant headache which I presume is due to liver trying to filter out high level of chemicals circulating and really bad abdominal pain and sore stomach. Feel sick and tired. Abdo pain means I need to lie down as worse when upright. Its not reflux as too low down right from base of ribs to caesarean scar! Plus I know what reflux is like and this is different pain.
I've had the same symptoms every day after MTX doses with no other change in my life so I put these developments on the MTX. If this is how it is going to be every week I'm not sure I can do it as it is very painful.
I have review with rheumy nurse on Tues to see how getting on. Last time she was as sympathetic as a sledgehammer so I feel apprehensive already. I asked for injection MTX not oral due to long standing stomach problem but she told me MTX does not affect stomach and just persisted with (cheaper for NHS) tablets prescription.
What can I expect at review? Will I have to persist like this for 12 weeks before thy will discuss options? So far my RA experience is of being left to endure things. Can I ask to change already?
I'm also on hydroxy Neither drug is showing much effect on joint pain or swelling. I am less stiff than i was but put this down to big dose of steroids still being in my system.
Feel beaten down by horrible side effects.