I have suffered with RLS for many years which affects my legs when I go to bed but have been fairly well controlled with Pramipexole. I have been taking Leflunomide for two weeks now and have noticed that my RLS symptoms have got worse. The last few nights have been really difficult and even after trying various things to get some relief it's still been about 2am before I can get to sleep. I am beginning to dread bedtime now not knowing whether my legs are going to be calm or if I am in for another restless night.
I would be interested to know if anyone else has noticed that their RLS has got worse when taking Leflunomide?