I have been taking leflunomide for about 3 months with no side effects, until now. I have ibs and for about 1 and half weeks I cannot get off the toilet. This is worse then my normal ibs I have had to come home from work and also go in late due to always needing the bathroom. I also feel a bit nausea at the same time. Anyone else had this while taking leflunomide? I am scared to go out in case I have a bad episode.