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Pramipexole

I have just changed my medication from Gabapentin to Pramipexole has anyone had experience of using Pramipexole for bad RLS.
I have just changed my medication from Gabapentin to Pramipexole has anyone had experience of using Pramipexole for bad RLS.
Mike-tyson profile image
Mike-tyson
in Restless Legs Syndrome
2 months ago

RLS and Parkinsons

Her body is not in great shape after years of parkinsons so unnecessarily subjecting her to weaning off the pramipexole would be a bad course to follow except that the long term effect of high dose pramipexole may be serious in themselves.
Her body is not in great shape after years of parkinsons so unnecessarily subjecting her to weaning off the pramipexole would be a bad course to follow except that the long term effect of high dose pramipexole may be serious in themselves.
Graham3196 profile image
Graham3196
in Restless Legs Syndrome
6 days ago

Pramipexole

I've been on Pramipexole for about 5years now. I take a very low dose of one .088mg tablet per night, but my doc says it's perfectly fine to take 2, as that would still be considered a low dose.
I've been on Pramipexole for about 5years now. I take a very low dose of one .088mg tablet per night, but my doc says it's perfectly fine to take 2, as that would still be considered a low dose.
Farmgurl1 profile image
Farmgurl1
in Restless Legs Syndrome
2 months ago
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Coming off pramipexole

I am currently on a half of 0.088 mg of pramipexole and 200mg of pregabalin and one zapain tablet. I have cut my daily dose of pramipexole to half and am going to go cold turkey due to augmentation. What can I expect ?
I am currently on a half of 0.088 mg of pramipexole and 200mg of pregabalin and one zapain tablet. I have cut my daily dose of pramipexole to half and am going to go cold turkey due to augmentation. What can I expect ?
Carolinetidy profile image
Carolinetidy
in Restless Legs Syndrome
1 day ago

Pharma Two B to Present Additional Positive Results from P2B001 Phase 3 Trial at 2023 American Academy of Neurology Annual Meeting

Results showed P2B001, a once-daily fixed-dose combination of low dose pramipexole and low dose rasagiline, showed comparable efficacy to marketed optimally titrated pramipexole, with significantly reduced sleep-related and dopaminergic side effectsData analysis also confirmed patients treated with P2B001
Results showed P2B001, a once-daily fixed-dose combination of low dose pramipexole and low dose rasagiline, showed comparable efficacy to marketed optimally titrated pramipexole, with significantly reduced sleep-related and dopaminergic side effectsData analysis also confirmed patients treated with P2B001
Farooqji profile image
Farooqji
in Cure Parkinson's
1 month ago

Transitioning off pramipexole

I keep reading the absolute hell many people experience transitioning from pramipexole (or some other drug) to gabapentin. The worst seems to be when one is essentially finished with pramipexole but have taken very little gabapentin.
I keep reading the absolute hell many people experience transitioning from pramipexole (or some other drug) to gabapentin. The worst seems to be when one is essentially finished with pramipexole but have taken very little gabapentin.
robertff3401 profile image
robertff3401
in Restless Legs Syndrome
2 months ago

Shortage of Pramipexole 0.18mg? UK

Currently I was taking 2 x Pramipexole plus 2 x 100mg prolonged release Tramadol per night for 5 nights and 2 nights per week taking 3 x Pramipexole only which was working and I was hoping to reduce pramipexole further.
Currently I was taking 2 x Pramipexole plus 2 x 100mg prolonged release Tramadol per night for 5 nights and 2 nights per week taking 3 x Pramipexole only which was working and I was hoping to reduce pramipexole further.
Felixstowe profile image
Felixstowe
in Restless Legs Syndrome
2 months ago

Archieb

can you take pramipexole as well as Pregabalin?
can you take pramipexole as well as Pregabalin?
Archieb48 profile image
Archieb48
in Restless Legs Syndrome
17 days ago

Oxycodone, Pramipexole and Codeine.

I was on 8 Codeine phosphate 30mg tablets a day and one Pramipexole 0.52mg modified release tablets at night. Now I am on the oxycodone I do not take the codeine phosphate tab or the Pramipexole tablet. I cannot take the pramipexol and the oxycodone at the same time. It seems like an overdose.
I was on 8 Codeine phosphate 30mg tablets a day and one Pramipexole 0.52mg modified release tablets at night. Now I am on the oxycodone I do not take the codeine phosphate tab or the Pramipexole tablet. I cannot take the pramipexol and the oxycodone at the same time. It seems like an overdose.
JoeR profile image
JoeR
in Restless Legs Syndrome
13 days ago

Reducing pramipexole

., which I'm usually fine with.Is the reduction in pramipexole likely to be the reason for the increase in persistent and very aggressive rls. Any ideas?
., which I'm usually fine with.Is the reduction in pramipexole likely to be the reason for the increase in persistent and very aggressive rls. Any ideas?
pennygates profile image
pennygates
in Restless Legs Syndrome
8 days ago

Pramipexole withdrawal

My scenario, I've been on pramipexole for the last 3 months with constant dose of daily one 0.25mg tablet 2 hours before the bedtime. If I decide to stop, should I taper off by 1/4 of the tablet for 2 weeks 4 times or just stop it "cold turkey"? Thank you, all.
My scenario, I've been on pramipexole for the last 3 months with constant dose of daily one 0.25mg tablet 2 hours before the bedtime. If I decide to stop, should I taper off by 1/4 of the tablet for 2 weeks 4 times or just stop it "cold turkey"? Thank you, all.
rls-ottawa profile image
rls-ottawa
in Restless Legs Syndrome
21 days ago

Pramipexole / Pregabalin

After many years on Pramipexole and having reached the max dose (6 x 0.88mg), I suffered augmentation and visited my GP. The GP i saw was very sympathetic and started me on Pregablin whilst I reduced the dose of Pramipexole..
After many years on Pramipexole and having reached the max dose (6 x 0.88mg), I suffered augmentation and visited my GP. The GP i saw was very sympathetic and started me on Pregablin whilst I reduced the dose of Pramipexole..
Ced60 profile image
Ced60
in Restless Legs Syndrome
2 months ago

Novel PD Drug Tops Pramipexole ER With Fewer Side Effects

A novel experimental drug for early Parkinson's disease (PD) yielded similar results as commercially available pramipexole extended-release (ER) but with significantly less daytime sleepiness, a new study shows.
A novel experimental drug for early Parkinson's disease (PD) yielded similar results as commercially available pramipexole extended-release (ER) but with significantly less daytime sleepiness, a new study shows.
Farooqji profile image
Farooqji
in Cure Parkinson's
1 month ago

off Pramipexole

But what I do know is that my symptoms were increasing as my ferritin levels dropped, but when I started taking the Sytner things improved at the same time tgat I came fully off the Pramipexole.
But what I do know is that my symptoms were increasing as my ferritin levels dropped, but when I started taking the Sytner things improved at the same time tgat I came fully off the Pramipexole.
RestlessMe profile image
RestlessMe
in Restless Legs Syndrome
1 month ago

Pramipexole update

Please note I was only on Pramipexole for six months and I only ever took two tablets per day. Any guidance would be much appreciated. Good luck to everybody else fighting this battle.
Please note I was only on Pramipexole for six months and I only ever took two tablets per day. Any guidance would be much appreciated. Good luck to everybody else fighting this battle.
Lineker profile image
Lineker
in Restless Legs Syndrome
1 month ago

pramipexole shortage

Why can they not continue relatively inexpensive and proven life-changing treatments such as Pramipexole. I just hope it has not been discontinued.
Why can they not continue relatively inexpensive and proven life-changing treatments such as Pramipexole. I just hope it has not been discontinued.
Grumpdad profile image
Grumpdad
in Restless Legs Syndrome
2 months ago

Replacing Pramipexole with Pregabalin

I was thinking that maybe a better option would be to slowly reduce pramipexole and introduce pregabalin over a month long time frame. Any comments or advice would be much appreciated. Thanks in advance for taking an interest.
I was thinking that maybe a better option would be to slowly reduce pramipexole and introduce pregabalin over a month long time frame. Any comments or advice would be much appreciated. Thanks in advance for taking an interest.
sidepocket profile image
sidepocket
in Restless Legs Syndrome
13 days ago

Pramipexole .125

I have been taking pramipexole for years for my RLS. I was prescribed .125 3X daily. I have weaned myself down to 1 pill at night. Can it still augment? Also, does Adderall affect RLS?
I have been taking pramipexole for years for my RLS. I was prescribed .125 3X daily. I have weaned myself down to 1 pill at night. Can it still augment? Also, does Adderall affect RLS?
pdpurdy54 profile image
pdpurdy54
in Restless Legs Syndrome
3 months ago

PLMD and pramipexole

I want to try and steer clear of pregabalin, amitryptaline or tramadol if I can help it but I’m worried that the pramipexole isn’t helping. Has anyone had a similar experience?
I want to try and steer clear of pregabalin, amitryptaline or tramadol if I can help it but I’m worried that the pramipexole isn’t helping. Has anyone had a similar experience?
Grandy1962 profile image
Grandy1962
in Restless Legs Syndrome
2 months ago

RLS Relief

RLS-at the outset I take 75mg of Pramipexole (Mirapex) which is used for Parkinson's. Within an hour, it works.
RLS-at the outset I take 75mg of Pramipexole (Mirapex) which is used for Parkinson's. Within an hour, it works.
LSGW profile image
LSGW
in Restless Legs Syndrome
3 months ago
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