Experiences with

Pramipexole

I have just changed my medication from Gabapentin to Pramipexole has anyone had experience of using Pramipexole for bad RLS.

Her body is not in great shape after years of parkinsons so unnecessarily subjecting her to weaning off the pramipexole would be a bad course to follow except that the long term effect of high dose pramipexole may be serious in themselves.

I've been on Pramipexole for about 5years now. I take a very low dose of one .088mg tablet per night, but my doc says it's perfectly fine to take 2, as that would still be considered a low dose.

I am currently on a half of 0.088 mg of pramipexole and 200mg of pregabalin and one zapain tablet. I have cut my daily dose of pramipexole to half and am going to go cold turkey due to augmentation. What can I expect ?

Results showed P2B001, a once-daily fixed-dose combination of low dose pramipexole and low dose rasagiline, showed comparable efficacy to marketed optimally titrated pramipexole, with significantly reduced sleep-related and dopaminergic side effectsData analysis also confirmed patients treated with P2B001

I keep reading the absolute hell many people experience transitioning from pramipexole (or some other drug) to gabapentin. The worst seems to be when one is essentially finished with pramipexole but have taken very little gabapentin.

Currently I was taking 2 x Pramipexole plus 2 x 100mg prolonged release Tramadol per night for 5 nights and 2 nights per week taking 3 x Pramipexole only which was working and I was hoping to reduce pramipexole further.

can you take pramipexole as well as Pregabalin?

I was on 8 Codeine phosphate 30mg tablets a day and one Pramipexole 0.52mg modified release tablets at night. Now I am on the oxycodone I do not take the codeine phosphate tab or the Pramipexole tablet. I cannot take the pramipexol and the oxycodone at the same time. It seems like an overdose.

., which I'm usually fine with.Is the reduction in pramipexole likely to be the reason for the increase in persistent and very aggressive rls. Any ideas?

My scenario, I've been on pramipexole for the last 3 months with constant dose of daily one 0.25mg tablet 2 hours before the bedtime. If I decide to stop, should I taper off by 1/4 of the tablet for 2 weeks 4 times or just stop it "cold turkey"? Thank you, all.

After many years on Pramipexole and having reached the max dose (6 x 0.88mg), I suffered augmentation and visited my GP. The GP i saw was very sympathetic and started me on Pregablin whilst I reduced the dose of Pramipexole..

A novel experimental drug for early Parkinson's disease (PD) yielded similar results as commercially available pramipexole extended-release (ER) but with significantly less daytime sleepiness, a new study shows.

But what I do know is that my symptoms were increasing as my ferritin levels dropped, but when I started taking the Sytner things improved at the same time tgat I came fully off the Pramipexole.

Please note I was only on Pramipexole for six months and I only ever took two tablets per day. Any guidance would be much appreciated. Good luck to everybody else fighting this battle.

Why can they not continue relatively inexpensive and proven life-changing treatments such as Pramipexole. I just hope it has not been discontinued.

I was thinking that maybe a better option would be to slowly reduce pramipexole and introduce pregabalin over a month long time frame. Any comments or advice would be much appreciated. Thanks in advance for taking an interest.

I have been taking pramipexole for years for my RLS. I was prescribed .125 3X daily. I have weaned myself down to 1 pill at night. Can it still augment? Also, does Adderall affect RLS?

I want to try and steer clear of pregabalin, amitryptaline or tramadol if I can help it but I’m worried that the pramipexole isn’t helping. Has anyone had a similar experience?

RLS-at the outset I take 75mg of Pramipexole (Mirapex) which is used for Parkinson's. Within an hour, it works.