I was diagnosed with RA in Feb. '14. After reading about antibiotic therapy, I talked my Dr. into letting me try it, while also taking Methylpred. He put me on Methotrexate, and after about three weeks I had to stop it due to my hair falling out, the worst headache I've ever had and the inability to concentrate. Then he prescribed Leflunomide, which after only two pills made my stomach hurt and hair fall out. Now I am (still) on Minocycline/Methylpred. I still have flares, stiffness and pain, but no more morning crying, and I understand that this therapy takes time to work. I feel better knowing that the Minocycline isn't toxic and I'm hoping that it will one day work the way I understand it to.