I saw my rheumy doc today after being on Enbrel alone for 5 weeks. He wants to start me on a low dose of SSZ because he says that Enbrel is not a mono therapy. I am terrified of this new DMARD since I was on MTX and Leflunomide in the past and both caused significant hair loss, crispy fingernails and made me feel and look old. My new hair growth is now about 3 inches long and I am feeling younger again. I really want to skip the SSZ. The Enbrel has been very effective since the first injection. However, on the 5th injection, I had a skin reaction and I am afraid my body might be rejecting it. Anybody have any advice or encouragement for me?