Variations in serum creatinine 10% in 2 weeks

[ionelcro]

Hello, my name is Ionel and I am new to this forum. I have a chronic kidney disease, stable for years with creatinine 1.09 mg/dl. Since March, I have been suspected of having IGA nephropathy, I have not had a biopsy yet. I lose proteins, approximately 500-700 mg/24h, red blood cells 15-15 hpf. In February, serum creatinine 1.09, I was given prestarium (perindopril arginine) and forxiga ((SGLT2) treatment. I took prestarium 0.25 mg daily, forxiga 1 tablet every 2-3 days. In April, creatinine increased to 1.16 mg/dl. From In April, I was given rosucard statins, prestarium 0.25 mg daily, and I take forxiga every 2-3 days, as well as statin. On June 20, the creatinine is 1.16 mg.dl. I saw that the creatinine has increased, but it is maintained within laboratory limits, I started taking forxiga one day, the next day I took rosucard statin, daily prestarium 0.25 mg. On July 1, serum creatinine jumped from 1.16 mg/dl to 1.26 mg/dl at the same laboratory with the same method. determination, jumping from values ​​(0.73-1.18mg/dl). What happened, my kidney function decreased in 2 weeks, or maybe it's because of the drugs, forxiga and statin, that I took forxiga one day, the next day statin and daily prestarium? Has it happened to anyone that the creatinine fluctuates by 10% in just 2 weeks? Is it because of the drugs or has the kidney function deteriorated? I'm afraid to redo the serum creatinine analysis!