Yes I am one that has Primary Progressive Multiple Sclerosis. I have had this now since 1999. So I have now had this for 18 years. It really has been a very hard to take illness. I have my Neurologist telling me that he is going to put me on this medication, Ocrevus. I was told it will not heal anything, but at least I will not get any worse. I am just happy with that. I do not want to get so bad that I would need to be bed ridden. I would like to get into some of the reading that I did read little on.