I've had ET for a couple of years, take 1gm Hydrea daily. I am getting horrendous mouth ulcers, often 3 or 4 at a time. The Haematologist has tried lowering my dosage, but my blood count goes up, so that's not an option. My zinc and B vitamin levels are normal. I have every medication on Boots' shelves to combat the ulcers, and some stuff from the US which is very effective for pain relief, but what I really want is to prevent them. Has anyone managed to do this?