Eylea

[GailGail]

I have been diagnosed with severe wet amd with severe vision lost. Had my first eylea injection. Am wondering if anyone else with severe vision loss had any success with Eylea treatments.

[Retired130]

I am in the USA, so my eye vision measurements are USA measurements.I have Wet MD in my right eye so all numbers are for just that eye. My vision from Wet MD was down to 20/200. Basically could just read the largest letter on the eye chart & that was it. Could not identify anything smaller.

I started on Avastin every 4 weeks for 15 months, but then the Avastin stopped working, so I was switched to Eylea. After the 3 load shots, each one month apart, I went to 6 to 7 week intervals. After about6 total shots, my vision improved to 20/100 and eventually after several more shots it got to 20/80. That is about the best it has gotten after about 4 total years of Eylea shots.

The most important thing is that the bleed has stopped & my vision is not getting any worse in that eye, so I am thankful for that. As for the interval, each person is different. As for me, my retina specialist tried extending the interval between shots, but at 8 weeks, the bleed returned & the vision deteriorated, so now I always get the shot every 6 to 7 weeks.

I hope this answers your question.

[BagelBrent]

Lucentis, Avastin & Eylea Injections for Macular Degeneration (kadrmaseyecare.com/therapeu....

With respect to treating wet macular degeneration, there have been some exciting new developments in the past several years. Three drugs, Lucentis, Avastin and Eylea, are used to inhibit the growth of blood vessels under the retina and help prevent further vision loss.

In technical terms, Vascular Endothelial Growth Factor (VEGF) is a protein that encourages the formation of unhealthy new blood vessels under the retina. These weak blood vessels can leak, causing the rapid destruction of the macula, and resulting in central vision loss. Lucentis, Avastin and Eylea work by inhibiting VEGF. Since they target wet AMD earlier in its development, they have a positive impact of preventing vision loss.

Lucentis, Avastin and Eylea are given to patients with active, leaky blood vessels, initially in a series of three (3) injections given four (4) weeks apart. In the interim, there will be close follow-up by your doctor. He / she may also schedule additional testing including fluorescein angiography, indocyanine green angiography, and optical coherence tomography to monitor the effects of the medication on the blood vessels.

Lucentis and Avastin are the first drugs that have actually demonstrated improved vision. Approximately 40 percent of patients treated with these drugs have improvement in their vision. In addition, 90 percent are able to stabilize their vision and prevent further vision loss. Eylea is a newer drug with similar efficacy. Some patients that don't respond to Avastin or Lucentis respond to Eylea, and vice versa.

Above, is a medical discussion on the use of injected medications. There are hundreds of such Medical websites that give such information on Eylea, Avastin and Lucentis. Avastin was a drug developed to treat cancer and tumors. Avastin destroyed the tiny blood vessels that fed the tumor and allowed it to grow. Very smart doctors realized Avastin could also destroy the blood vessels that feed the drusen that grows on your macula. They tried the Avastin as a treatment for wet macular degeneration. Avastin worked! I have wet macular degeneration in both eyes. The disease is stabilized. I currently receive injections every 7 weeks. Open your computer and read about the treatment available for your eyes. The new developments that are coming. Ultimately, you are responsible for your own health. Wishing you the very best!

[rosyG]

Eylea is working well for me. I hope you get good improvement.

[GailGail in reply to rosyG]

How bad was your vision when you started? Thanks

[GailGail in reply to rosyG]

How bad was your vision when you started? Thanks.