First I will say I am being treated for Lupus but have no dx yet. I have had rash on both hands, palms and some on fingers, little water blisters. I have had this before but only for a day or two and the it is gone. This has been going on for 3 weeks now and when I think it is getting better it starts over again. If lupus related, could this happen by decreasing Plaquenil, which was doctors suggestion. He wanted to see what would happen, is this something he would like to know?