silent reflux and methotrexate

[Lovemydogs1]

Hi

I am a long time methotrexate user and have just been diagnosed with acid reflux. I have been put on 40mg Omeprazole. Is anybody else on both?

I am worried about my kidneys and also my joints and muscles due to omeprazole leaching vitamins.

I am on 20mg Methotrexate.

Thanks

[CarolMcl]

Hi I take both. I've been on omeprazole for years now and I think methotrexate for about 5 yes and not experienced any issues taking both 🌹

[Lovemydogs1 in reply to CarolMcl]

thanks

[HazelW]

I was on both for years with no bad effects but have had to stop metho for the time being as I have recently had a mastectomy and was starting chemo, but the chemo was deemed too aggressive so we are moving on to radiotherapy. Still taking Omeprazole though.

[Lovemydogs1 in reply to HazelW]

thanks for your reply but very sorry for your health issues

[HazelW in reply to Lovemydogs1]

Thank you, but at least I'm still here to to talk about it and I AM 76 !!! 💜

[Lovemydogs1 in reply to HazelW]

very true

[Krazykat26]

I was prescribed omeprazole to protect my stomach from prednisolone in 2017. I started methotrexate in 2019. I'm still taking all of them today and I've had no problems. I was told to take omeprazole about forty minutes before I take my pred...this gives it more of a chance to protect my tummy before I take my 4mgs of prednisolone. I'm currently on 10mgs methotrexate weekly. Good luck with it..I hope it helps 🍀💜🦋

[Lovemydogs1 in reply to Krazykat26]

thanks for your reply

[FandNnan]

Me too at one time and no problems. However methotrexate stopped for unrelated reasons at one point so I now take Azathioprine plus other medications and still take omeprazole twice daily. 😊

[Lovemydogs1 in reply to FandNnan]

thanks for reply

[Jerg]

I only take Methotrexate and vitamin D and folic acid. I usually take 6 tablets a week now only 3 .

I do not have any issue with it

[Murp17]

Hi I take both methotrexate and omeprazole twice a day and have no more problems

[Lovemydogs1 in reply to Murp17]

thanks

[hearm]

yes I am on 10 methotrexate and 30 omeprazole. Tried to take myself off ppi for similar concern as yours. I have been really nauseous and fatigued for 12 days now and have gone back on ppi !

[Lovemydogs1 in reply to hearm]

thanks

[Lovemydogs1]

thanks

[Lily25]

Hi I've been on Omeprazole for many years and methotrexate for 6 years. I'm absolutely fine with both. However I do take a lot of supplements and try and eat a healthy diet as possible.

Good luck

[Lovemydogs1]

thank you. Can I ask do you take a magnesium supplement at all?

[SoooManyQuestions]

I'm in a similar situation, but take famotidine instead of omeprazole. The latter caused me migraine-like headaches. In case you have similar issues down the road! I've been on it long term, 20-40 mg daily over several years, depending on my symptoms, and it's been fine.

[Lovemydogs1]

thanks that’s interesting. I have been considering whether to ask the doc to change to famotidine. Does it help the reflux?

[Poshcards]

I was on 25mg metho and omeprazole for years, approved by my excellent rheumy x