Lupus sle treatment

[Emz04]

Hey everyone I was diagnosis in may lasy year I'm on hydroxychlorquine 200mg twice a day steroids 15mg azathioprine 100 which has been incresed to 125 for 4 weeks and the 150 after that and 3 times a week I'm on Mepacrine for 3 months then that will become daily anyone else on mepacrine? Anyone found something better then mepacrine I'm not liking he yellow side effects of it and I'm still fatigued and nausea started again

[Happykins]

Hi Emz04,

I've been on Mepacrine since 2014 as appeared allergic to hydroxychloroquine.

I take 100mg/50mg on alternate days.

I'm rather golden and my big toe nails have blueish/black marks, tiny blue marks on middle finger nails.

It was difficult to find any info on Mepacrine 10 years ago.

I'll be interested to hear how you get on with it x

[soul22]

Hi sorry to hear of your diagnosis,Though I'm sure u glad to have diagnosis.

I was offered mecaprine but rheumatology consultant decided no for those allergic hydroxchlorquine or more severe lupus.

As it can cause jaundice re yellow skin affect liver

One doesn't usually have mecaprine and hydroxchlorquine usually one or other.

Also not allowed in London 400 mg total hydroxchlorquine because patients on that get eye sight issues.

I'm only allowed 200 mg not enough but won't adjust

Azathioprine I got to much infections to low immunity so it was stopped I switched methotrexate

Sun block I use all year as certain indoor lights and sun trigger a lupus flare/ sytpoms.

All best

[tiredmum]

I take 50mg of Mepacrine 3 times a week, also on 400mg hydroxy and 1500 mg mmf twice a day.

I had upset stomach from the mmf but thankfully no side effects from the Mepacrine.

Even with all of these meds I still suffer terrible fatigue, it’s debilitating.