Can positive report change to negative if turns i... - LUPUS UK

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Can positive report change to negative if turns is they are safe now from lupus

Rashmitha234 profile image
9 Replies

Hii everyone my sister is suffering from lupus from 1 and half year 2days back in ANA,DSDNA reports came negative plz help me in clarifying about that is lupus positive or negative now.plz any one give clarification about that positive report turns to negative reports is she safe from that disease

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Rashmitha234
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Ianrussell69 profile image
Ianrussell69

All I can say is I’ve probably had 5/6 tests some positive some negative and it’s very confusing ask consultant why and he said it was very common to have positive and negative results but did not really tel me why

Rashmitha234 profile image
Rashmitha234 in reply toIanrussell69

Thanks for ur information

AmyJ3 profile image
AmyJ3

Hiya, not too sure, I've only had one set of bloods and they've been positive but I've heard of many people with negative results but have lupus, and a small % of people with a positive ANA are perfectly healthy and don't have lupus.

But, does your sister have symptoms or had symptoms? Also, does she know how concentrated the dsDNA or the ANA was in a ratio?

My rheumy said to me the higher the ratio, the more significant the result and the more likely the rheumy thinks it's lupus. For example 1:20 is a low result, while 1:1600 is quite high.

If the result was low and she has never had symptoms, she may be the small % that don't have lupus.

However, if she has lupus symptoms her lupus could just be well managed perhaps? I've never heard of lupus completely disappearing.

The best bet is getting her to clarify with her GP or rheumy.

Good luck!

Rashmitha234 profile image
Rashmitha234 in reply toAmyJ3

Thanks for ur information

whisperit profile image
whisperit

Hello Rashmitha,

The values that we get from some of these tests - for example the dsDNA test - can vary depending on how active the disease is. So typically the values are high before treatment, but may decline after treatment. Unfortunately, low values don't usually mean that the disease has completely gone away for ever, just that it is well controlled.

But obviously, you will have to discuss this with your clinician to get a proper interpretation of what the results mean in any individual case.

x

Rashmitha234 profile image
Rashmitha234 in reply towhisperit

Thanks for ur information

granmyty profile image
granmyty

I was diagnosed with Lupus (SLE) about 40 years ago, but I moved and started with a new Rheumatologist and my test came back negative. Over the 40 years whenever tested I was tested positive. I still believe I have Lupus and will ask to be tested again in the near future.

Rashmitha234 profile image
Rashmitha234 in reply togranmyty

Thanks for ur information

Chanpreet_Walia profile image
Chanpreet_WaliaLUPUS UK

Hi Rashmitha,

Welcome to the LUPUS UK HealthUnlocked Community!

We offer a free information pack which contains factsheets, guides, a list of helplines and a list of LUPUS UK contacts who you or your sister can chat to over the telephone. To download or request this pack please click here: lupusuk.org.uk/request-info...

Has your sister already been diagnosed with lupus?

And is she able to discuss her results with her doctor?

An ANA test gives an indication on whether a person may or may not have an autoimmune condition. It does not provide sufficient evidence to confirm a diagnosis of lupus. About 5% of people with lupus have a ‘negative’ ANA result.

Although dsDNA antibodies are very specific for lupus (as they are not typically seen in any other condition or in healthy population) only approximately 60% of people with SLE will test ‘positive’. Therefore if someone is positive for these antibodies, it often means they have lupus, but if they are negative it does not necessarily mean they do not have lupus. For more information, you can read our blog article on ‘getting a diagnosis of lupus’ here: lupusuk.org.uk/getting-diag...

It is possible for people to experience periods of remission where their lupus is controlled and they feel relatively better; reducing the signs of their symptoms.

Wishing you and your sister all the best, please keep us updated.

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