Hello, I have had very elevated CRP, ESR and platelet counts for about 2 years. Elevated c3 and c4 negative ANA and low Vit D. They have suggested Undifferentiated Connective Tissue Disorder and now Spondolaropathy. I have light sensitivity, migraines, arthiritis, tendonitis, Raynards syndrom and several other joint problems. I was thinking it was lupus but have not tested positive for ANA. They have tried, sulfasalizine, methotrexate, and CellCept, nothing has improved my inflammatory markers or symptoms. The last few months I have had a skin rash that was diagnosed as Pruritis Nodulares. The doctors are at a lost to figure out the problem. The waiting and guessing has taken a serious toll on me and my previously diet controlled diabetes has gotten out of control. Now, I am on 3 meds just for that. I am at my wits end to what this could be.