Can hyperlipidemia cause Hughes Syndrome?

[HUVB]

I was just recommended to this site because I mentioned that 23 years ago (at age 36) my then cardiologist said along with my off the charts lipids, that my blood was "so sticky that they could not even get a real true accurate lipid count." I have assumed that it has been the statins and fibrates that have "unstuck" my blood all this time. Could extreme combined familial hyperlipidemia alone cause "sticky blood" or should I ask for a Hughes Syndrome blood test.

[GinaD]

Are you having any symptoms that might be attributed to Hughess? Migraines, tingly feelings, rashes, constant fatigue( DVTs)?

[Jumper99]

Having sticky blood does not mean that you have APS. APS is just one reason for sticky blood. Your high lipids would cause your blood to clot more easily which is what sticky blood means.

I’ve not come across your condition before and I’ve never heard of it as a trigger for APS but you can never tell with APS as it’s not that well understood.

As you are aware of the condition and it’s potential for causing blood clots then I think you would worry that you had APS even if you had none of the more minor symptoms. So if I were you I would ask for the blood tests to be done. There are three blood tests you should have called lupus anticoagulant (it’s a test for APS not lupus, just badly named), anticardiolipin antibodies and anti beta2-glycoprotein1

If any one of them is positive it should be repeated 12 weeks later. You only need one of the 3 tests to be positive not all three but all three should be done.

[HollyHeski Administrator]

Not necessarily- have you had any clotting episodes? but if you think you have Hughes/ APS , then worth getting the blood tests done. For positive diagnoses 2 sets 12 weeks apart.

google.com/url?sa=t&source=...

[1sam]

Hi. There are different diseases. Hughes Syndrome or Antiphospholipid syndrome (APS) is an autoimmune disorder. It can have many triggers but it is not caused by having high lipids.

Can someone have both? Yes, possibly.

Treatment and diagnosis are different for each; antibodies tests and coagulation times are typical to verify APS, history of past clotting events is important too.

If you have symptoms I would suggest you to be tested... I'm adding a couple of links so you can read some.

nhs.uk/conditions/antiphosp...

rarediseases.info.nih.gov/d...

[MaryF Administrator]

Hi there is really no reason not to have the tests, (3 tests), to rule it in or out, many of us have overlapping diseases. The three tests are here:

anticardiolipin,

beta-2 glycoprotein I (β2GPI),

lupus anticoagulant

If your GP thinks you have, we can try to send you an idea of the specialists nearest you. MaryF

[Splodge60 in reply to MaryF]

Please could you do that for me MaryF

[MaryF Administrator in reply to Splodge60]

Give me an idea of your area, thanks. MaryF

[Splodge60 in reply to MaryF]

Lancashire above Manchester