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Hughes Syndrome APS Forum

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bhaskar2boda profile image
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Can aps syndrome patient have positive ANA test......and symptoms free of lupus so that why am asking question is .....in 2013 am diagnosed with acL igm positive and ANA positive....am on warfarin therapy up to now....am asking doctor what was ana positive mean I have lupus....they said u r symptoms free of lupus that's why u don,t have lupus....my doubts is can ANApositive later turn in to lupus...please answer my questions

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bhaskar2boda
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MaryF profile image
MaryFAdministrator

Once you have one autoimmune disease you can then go on and develop others later, for instance, it took me a while to test positive for Lupus and also for Hughes Syndrome/APS, even though I was highly suspected of having them. A positive ANA is just one part of the diagnosis. MaryF

bhaskar2boda profile image
bhaskar2boda in reply toMaryF

Madam....lupus turn into aps....but not aps turn into lupus...on Google it say aps not turn into lupus ....is it correct

MaryF profile image
MaryFAdministrator in reply tobhaskar2boda

They are different diseases, but related like cousins. MaryF

bhaskar2boda profile image
bhaskar2boda in reply toMaryF

Madam.....am i have positive ANA in 2013 ..and anti ds DNA negative...my question is ana positive can cause lupus in other times....and my second time I.e after 12 weeks...my acL antibody igm negative...but my question is can positive ANA homogeneous cause lupus later...tel me

KellyInTexas profile image
KellyInTexasAdministrator in reply tobhaskar2boda

There is primary Lupus, and primary APS with “features of Lupus” because, as Mary says, APS and Lupus are in the same family. They are indeed like cousins.

A positive ANA does not necessarily mean you will definitely go on to develop full lupus along with your APS. It does mean you should be closely watched, like all of us.

It is important you be placed on Hydroxychloroquine. ( plaquinil) as it can slow down the progression of lupus, Sjögren’s, and other Autoimmune diseases that have a tendency to join up with APS ,” by as much as 10 years” according to my APS specialist in San Antonio, Texas.

Dr Graham Hughes releases a Venn Diagram detailing the relationship between SLE and APS . I posted a photo of this just a few weeks ago. If you click on my information, you will find my posts. Scroll down to the one titled Venn diagram- overlap of SLE and APS.

bhaskar2boda profile image
bhaskar2boda

Seronegative lupus .....madam ..am not have lupus symptoms when ANApositive test done 2013 up to now....can it be lupus without symptoms

lupus-support1 profile image
lupus-support1Administrator

There are many people with a positive ANA but do NOT have SLE!

Positive ANA doesn’t diagnose SLE; a diagnosis is based on a clinical evaluation over time, which includes blood tests.

I have SLE but never had a positive ANA! Blood tests alone cannot diagnose & are not specific or sensitive enough, which is why you need a lupus specialist. Not all rheumatologists are experts in SLE.

With good wishes,

Ros

GinaD profile image
GinaD

I had a positive ANA for most of my life. But I have never been diagnosed with lupus, though I do have APS. My physician Father ( who did have lupus) told me that a positive ANA serves as a suggestion to treating physicians to pay extra attention to symptoms. So, don't worry! Antibody test numbers come and go.

What I have found is that consulting with a functional med specialist, with detailed blood tests and a detox/ elimination diet pointed us all to an unknown food allergies. Me? ( As I have written here before, but still add because I remain amazed, ) CASHEWS! Not walnuts. Not almonds. Not Brazil or macadamia. Cashews! Also gluten, ( but I figured that one out myself.) But since eliminating these foods all my antibody blood markers -including ANA--have fallen to what one hematologist calls "boring." ( I think " boring" is nice. Don't you?)

The advantage of Functional Med is that they are trained to look for systemic roots of illness.

kiminabmw profile image
kiminabmw in reply toGinaD

GinaD, how did you determine it was just cashews? Eliminate and reintroducing cashews resulted in physical symptoms and improved blood test results? I find this very interesting and would like to know more please.

GinaD profile image
GinaD

First, the doctors ran a lot of blood tests most doctors dont even know exist. They also placed me on a elimination/ detox diet that strongly eliminated a lot of stuff. Then, those blood tests came back. Based on those results they theorized I was allergic to some high histamine food: tomatoes, eggplant, cashews. These were added to my elimination /detox diet. After some weeks I began to reintroduce foods, one at a time, according to a schedule. and I was hoping --please don't be tomatoes, please don't be tomatoes! But I added tomatoes and had no problems. Eggplant? No problem. On the first day of reintroducing cashews I had bloating, gas, fatigue and the next day, all of above plus extra toilet trips, Based on that it was obvious that it was cashews which were the silent allergen. And now

I exhibit all those boring blood count numbers. I remain on warfarin, perhaps due to paranoia, but I am asymptomatic even when my INR dips below 2. ( Back in the day I needed to be between 3-4. )

GinaD profile image
GinaD

I will add that it was the specific blood tests which cued the doctors to a histamine reaction. functional medicine follows a very personal presentation. Treatment is based on each individual's specific symptoms and test results.

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