I have APS (diagnosed as primary obstetric), hashimotos & coeliac disease, also fibromyalgia. I'm not currently under the care of a consultant for my APS. My gastroenterologist, for my yearly coeliac check up, orders loads of bloods. Some of them are not specifically coeliac related but autoimmune generally eg thyroid tests. He also orders immunoglobulins.
On the past couple of occasions, my immunoglobulins igG and igM have been raised. Not vastly, but high nevertheless. I'm getting no joy out of the gastro as to why this is (my appointment is with the dietician and she has emailed & phoned him, but no answer is forthcoming). In coeliac disease, it is common to have igA deficiency apparently, not raised immunoglobulins.
My private doctor who I see about the fibro & thyroid is concerned I should have further tests. Myeloma (blood cancer) can cause raised immunoglobulins (eek!) as can autoimmune connective tissue disorders. At the moment,mint looks like I'm going to have to have the testing done privately, as I'm not getting anywhere with the NHS, but I will continue to fight!
My question here is, does anyone have raised immunoglobulins 'just' with APS ie those who don't have lupus/sjogrens/RA etc? Or do you think this is suggestive that I might have a further AI condition?
I've had weak positive tests for ANA and RF in the past, as well as anti-dsDNA, which was put down to the APS (also the specific abs for APS & miscarriages).
My ongoing symptoms, despite optimal management of my thyroid & coeliac disease and treatment of adrenals, gut issues etc are ever worsening joint & muscle pain, disabling fatigue & low grade depression.
Wondering if these bloods and symptoms are down to APS or another AI? Prof K didn't think I had lupus etc when he saw me when I was originally tested a few years back.