I was diagnosed with Factor V Leiden in 2013 when I received an injury playing softball causing me to have a DVT. I was put on lovenox then on Coumadin. The swelling never went away on the Coumadin however it did on Lovenox. I was taken off Coumadin in 2014. Recently without injury I have developed another DVT in the same leg. I was once again put on Lovenox and swelling went away. I was then put on Eloquis and in 24 hrs the swelling was back. I'm back on Lovenox and less the 24 hrs, swelling is gone. I was told no other blood test is needed due to it would.just shown have other stuff in my blood. I'm on a diet to lose weight and doing well. There are 14 females, same side of family that have Factor V Leiden. Recently my PCP asked about my water retention, joint pain, increased sensitivity to sunlight. I was confused. I went over health history with my Aunt just last night. Same side of family with Factor V Leiden I have 2 aunts that had Lupus, also RA runs rampant, cancer, and diabetes. Any suggestions on how to get my PCP or Hematologist to look past just my weight (which I've lost 15lbs already) and see if other issues may be causing my slowly developing issues. I'm very active, swimming, softball, fire fighting, hunting, camping, helping with friends with farm, etc. Any suggestions are welcome! I just want fixed to reduce my issues.