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Sticky Blood-Hughes Syndrome Support
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How do antibiotics affect warfarin contrilled inr?

Had a week on amoxycilin for laryngitis. Had venous blood test today to check and its fallen from 2.4 to 1.4. Nothing lese has changed, but have started on what I think is a lupus flare. Any thoughts on whats made my blood change? Thanks

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It would appear with some, that INR goes up and down with virus/infection and or antibiotics, so keep a close eye, it will however probably settle down again. MaryF x

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Thank you Mary. Still new to this. I guess I assumed antibiotics would increase my inr.

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Hi Bonnie 1.4 doesn't sound good, hopefully the Doctor has put you on fragmin as you were on it before until your INR comes up again.

What did the anticoagulant clinic say ?

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Hi Bonnie

I think than can do both.

Dave

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Thanks again. I am quite worried because the anticoag nurse has asked me to increase warfarin from 7mg daily to 7 and 8 on alternate days and then test again next Tuesday. The fragmin bridge may have been wise. Should I check this tomorrow?

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Speech has been really slurred and I am forgetting words, as well as having bad headaches and disturbed vision and dizzy spells. These problems have hit me from time to time but not since diagnosis so I'm a bit worried.

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Antibiotics always affect my inr. The ones I had recently brought it down.

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Antibiotics can be a bit of a problem and some more than others. Did you look on the PIL to see if it said anything about warfarin? I would call your anticoag clinic to ask about bridging with Fragmin if your symptoms are continuing to be worrying. I would also get some sort of emergency plan in place so that you have a supply of fragmin to take automatically when your INR drops below a particular number. That way you feel safe and your anticoagulation is protected until your INR comes back up.

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Hi when i have antibiotics my INR drops very low but mine is always a struggle to keep to 4.5/5 anyway i have to have bloods taken twice a week for life and my readings are always all over the place . x

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