Have seen my new GP this morning, what a lovely lady! She confirmed that my last GP had done the Lupus anticoagulant test which was normal but none of the others. Because she didn't have my medical records yet she couldn't order blood tests but has referred me straight to a rheumatologist to discuss my symptoms and family history, they can then do the tests. Can't believe what a difference a GP makes!!!
How many others of you have had neg Lupus anticoagulant and positive on the aCL or anti-B2GP1?, would it need to be positive on all three tests for a diagnosis?
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PepperT
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I have positive LA but negative on the others, weird but true! I do have APS and other conditions. Any of the three tests, positive 12 weeks apart are considered enough along with clinical symptoms!
Some people however, are negative on all but may be diagnosed on clinical symptoms, this is sero-negative APS. The trouble is that knowledge of APS, in particular sero-negative APS is patchy to say the least.
Take a look at hughes-syndrome.org for info to take to rheumy or other docs.
Diagnosis can be a troublesome journey, (may be an understatement) but once there and with correct treatment, APS can be dealt with.
I have tested positive for B2GP1 however now neg, but positive on the tvst for APS so confirmed diagnosis there, but negative on LA, although getting more and more symptoms, so just been re-tested as have rash up my legs that they think either micro thrombosis or vasculitus waiting fr results and biopsy
Hope you are ok
Lesley
I tested negative for the lupus indicator, and positive for only one (can't remember which) of the others. Can this change? As Lesley said she is getting a retest, does that mean you could have different positives later?
I have consistently had negative lupus anticoagulant and positive aPL and anti-B2GP1. I was told by a rheumy that LA will be negative if you are on Coumadin, and by another rheumy that LA may not be negative but cannot be accurately tested when you are on Coumadin. Does anybody know if this is true?
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Lupus Anticoagulant testing while on Warfarin
Treatment for lupus anticoagulant positive patients.
I tested positive for lupus anticoagulant, but retest a few months later is negative. I have MS like sx - not dx with anything at the time 
Lupus anticoagulent test 
\"warfarin can lead to false-positive test, but not false-negative tests\"
