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Why your INR target range is what it is (or should be) but no mention of Hughes Syndrome/APS, Lupus or Sjögrens

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British Society for Haematology recommended therapeutic intervals.

Prophylaxis of deep venous thrombosis (DVT), including high risk surgery: 2.0-2.5. Prophylaxis of DVT for hip surgery, surgery for femoral fracture; treatment of DVT, pulmonary embolism, transient ischaemic attacks: 2.0-3.0. Recurrent DVT and pulmonary embolism; arterial disease including myocardial infarction, arterial grafts, cardiac prosthetic valves and grafts: 3.0-4.5.

The European literature recommends an INR of 2.5-4.8, with a level of 3.6-4.8 for mechanical valves.

Source:

frca.co.uk/article.aspx?art...

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