Preclinical: RPT04402 to reactivate PP2A - Fight Prostate Ca...

Fight Prostate Cancer

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Preclinical: RPT04402 to reactivate PP2A

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Promising approach for multiple tumors (even if in its early stage).

RPT04402 is a first-in-class molecular glue that selectively reactivates PP2A, a tumor suppressor enzyme crucial for regulating cell growth.

By restoring PP2A activity, this therapy suppresses oncogenic pathways, offering a novel approach to address treatment-resistant prostate cancer.

Preclinical studies show its potential to slow or reverse tumor progression, making it a promising strategy for advanced cases. An Investigational New Drug (IND) application is expected by the end of 2025, paving the way for clinical trials.

prostatewarriors.com/2025/0...

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