Preclinical: Will bacteria save us?? ... - Fight Prostate Ca...

Fight Prostate Cancer

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Preclinical: Will bacteria save us?? A new amazing tool!

Maxone73 profile image
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Researchers at UMass Amherst have developed BacID, a bacteria-based cancer therapy that uses genetically engineered, non-toxic Salmonella to target tumors and deliver therapeutic agents directly into cancer cells. The bacteria, administered intravenously, preferentially colonize tumors and release their drug payload only after being triggered by aspirin.

This precise mechanism minimizes harm to healthy tissue and avoids the severe side effects of conventional treatments like chemotherapy. Preclinical studies have shown significant tumor reduction and long-term immunity in models of high-mortality cancers such as pancreatic and metastatic breast cancer.

Clinical trials are expected to begin in 2027, offering a promising new approach to treating aggressive cancers (no prostate at first but it's a pan-cancer solution).

umass.edu/news/article/rese...

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Maxone73
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Derf4223 profile image
Derf4223

Thanks max

Maxone73 profile image
Maxone73 in reply toDerf4223

You are welcome!

KocoPr profile image
KocoPr

Cool idea. I just thought of something. Since UMASS is a state government institution then shouldn’t it be able to bring this new drug or procedure to FDA approval without astronomical costs.

I’m pretty sure some pharmaceutical will fund it and get the rights to it and the institutions will get it share. Thus it will cost much more than it should. Just my conical thoughts.

Maxone73 profile image
Maxone73 in reply toKocoPr

They are already partnering with a pharma company to move it to phase 1

dhccpa profile image
dhccpa in reply toKocoPr

I suspect there ain't no such thing as a cheap new brand name drug. Would violate U.S. Constitution. I forget the section.

Maxone73 profile image
Maxone73 in reply toKocoPr

TBH I think about organizing a kind of charity to support at least phase 1 research, but not of a number of projects (for that I already donate to a couple of organizations), something really targeted, and possibly (don't ask me how) a kind of "fast lane" for the people who contributed to the financing...like those perks they use in crowd funding

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