Can anyone please give any positive comments on Sertraline. My doctor thinks it will help with my pain and fatigue. I’ve been on 25mg for a few months and after the first horrific week ( side effects ) things settled down and I have been calmer. However flares are frequent and unpredictable so have now started taking 50mg. Once again I’m really struggling with the side effects. I haven’t moved from bed or sofa for almost a week! I’m going to keep going but just need some reassurance that these side effects will pass and will help. Would really appreciate hearing from anyone who has gone through similar experience and come out the other side. Thanks and I hope everyone is as well as can be.