Fibromyalgia Action UK
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New med

Hi people

A warm Tuesday where I am.

Managed to get a GP appointment on line for earlier today.

We discussed getting too familiar with meds.

I am going to change at least temporarily from Citalopram to Fluoxetine.

Has anyone got 1st hand knowledge of taking this mild anti depressant? How long does it take to work as muscle relaxant?

Any reduction of my present symptoms would be welcome.

7 Replies

Hi skit

It is certainly a very strange day today. Very humid.

I have personally tried both of these antidepressants. Unfortunately I couldn't get on with either of them due to the rotten side effects I had.

To be completely honest I do struggle with antidepressants and antibiotics and have tried many different ones.

It just goes to show that what works for one person doesn't work at all for another, and can in fact have the opposite effect.

I take one of the older antidepressants Mirtazapine.

As a general rule of thumb antidepressants can take anything up to 6 weeks to start working, although they do tend to start working sooner than that.

I'm sorry this isn't more positive. Just out of interest have you ever tried Amitryptyline?

Good luck with the new antidepressant. I hope that it works well for you.

Wishing you less pain and more peace

Lu x


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I recently changed from Citalopram to Duloxetine which is an antidepressant but is also prescribed for Fibro. In my opinion you should change to Duloxetine instead as its been proven to be beneficial for people with Fibro. I've had friends who have been prescribed Fluoxetine some had bad reactions, it is Prozac & an SSRI (works on Serotonin only). Duloxetine is a SNRI, found this online re SNRI meds: "Serotonin and norepinephrine reuptake inhibitors (SNRIs) are a class of medications that are effective in treating depression. SNRIs are also sometimes used to treat other conditions, such as anxiety disorders and long-term (chronic) pain, especially nerve pain."

Everyone is unique and different antidepressants work differently on different people because our brain chemistry is different. From the people I know with Fibro I would recommend you try Duloxetine instead but please remember this is only my opinion. Let us know how you get on.

Peace & Hugs



I would never go on duloxetine again in my life, I was put on them in May I think, and I ended up having breathing difficulties and losing who I was. I knew what was going on in my body wasn't right, after all we all know our own bodies. So what did I do, I stupidly stopped taking them and omg I've suffered since with withdrawals and I mean suffered. I think it's up to you to do your homework on tabs especially if like me your not good with antidepressants. I always start them in the evening as if I'm going to have a bad reaction with them I'd rather it was when I'm sleeping until they get in my system. Sadly duloxetine and me didn't get on but that's not to say they won't work for you. I wish you all the best whatever you decide to do. Take care ❤️X

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When I was out on antidepressants for my back pain and insomnia I was told I should start feeling some effect by 2 weeks and the full effect by 6. Unfortunately like BlueMermaid3 they don't suit me so had to come off the two I tried. Do hope the switchover works for you.x

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Hi skit , I take Citalopram but was on Amitriptyline. If I had my choice I would go back, may talk with Dr about it on Friday.I wish you the best. Peck.🐤

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I am on fluoxetine and Amatriptyline, wouldn't say either of them help much. Sleep a bit when Amatriptyline is increased then back to normal. I was originally put on fluoxetine to help with symptoms of menopause but did nothing for that either. GP review is due so hopefully might get something else - sorry this doesn't help your situation any xx

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Hi my friend

I have never tried this medication myself but I want to sincerely wish you all the best of luck with it. Please take care of yourself.

All my hopes and dreams for you



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