Good afternoon all, after 5 years TTC and 3 losses we had our precious little boy last year. We have 3 embryos in the freezer and hoping to use them soon as it took us so long the first time! I am however very anxious at the idea of trying again and going through any more loss. I was just wondering if anybody has had any success with trying for number 2, the clinic has advised that we do a constructed cycle for the best chance but also very reluctant to have more injections π so I guess this post is more looking for advice/support?!
Trying for #2, anxious! : Good... - Fertility Network UK
Trying for #2, anxious!


Hello lovely,
I'm in a similar situation to you - we had 5 embryos in the freezer after having success on our 6th go.
We did our first transfer for #2 in November 2023 and I was floored when it didn't work - I just assumed if we used the same protocol (we did immunology as that ended up being the main issue) it would work but nope.
2nd transfer I had a very late positive but it faded the following day.
For the 3rd one I read that if you already had high immunity it can be even higher after a successful pregnancy so I upped my steroid dose, and also did a course of doxycycline to clear out any infection in the uterus - and it worked. Sadly we had an mmc at 6+4 but at least we got that far.
We're about to embark on number 4 and 5 - then we'll call it a day. Like you I'm done with the injections!
So no positive story for you yet, but fingers crossed for us both xx
Thank you for your reply! Praying #4&5 make it to your arms π
I think I am more anxious at the fact that we actually finally had a baby and in my head, I'm just expecting the next one will work but in reality I know that nothing is ever that simple! It's already been such an emotional rollercoaster and I am unbelievably blessed so hesitant to go through any more heartbreak.
I completely felt the same - to be honest going back in to it again after an mmc is filling me with dread. I can't imagine being able to cope with the wait for scans etc - and that's assuming that we get a positive. It's all so hard isn't it - but I'm not ready to give in so I need to pull up my big girl pants and get on with it.
I have everything crossed that your first one works - and no more heartbreak xx
I had my daughter on my second cycle of ICSI in July 2020. We had one frozen embryo left from that cycle. In December 2022 we started the process of trying for a sibling. Started meds for FET in Jan 2023 but after a week they found a polyp so treatment stopped and I then had to go through the NHS to have sorted. Had that removed in June, although it ended up being tiny and the consultant that did that didn't think it would have been an issue for implantation.
In that time our clinic was shut down by the HFEA for various reasons, we lost faith and so decided to move clinic which was complex and took a few months. In September 2023 attempted FET at new clinic but by this time the stress got to me and I had become unwell with a dizziness problem....so abandoned that too.
Got better after a few months, then finally had FET in Jan 2024 but it was BFN.
I had to lose some weight so spent a few months on that and then did a new cycle of ICSI in July, this gave us one good embryo which I had transferred and I'm now due a boy in just under 8 weeks time.
I think getting started is a good idea, it may work out straight away so you'll be busy but if there are hurdles then hopefully it doesn't delay you getting to where you want.
I didn't have the issue with MMC like you so I appreciate I didn't have the same journey, but I know that rollercoaster of emotion, it has definitely taken its toll on me in the last couple of years. I'm obviously very lucky to be in the position I am, but at the same time it's like the stress of the recent years has slightly tainted my enjoyment and excitement if that makes sense.
I wish you all the best of luck with your treatment, you've got there once so the chances are definitely with you to do it again π
Nope, I guess most of us here are still waiting for #1