APS antibodies - clexane dose?

[Endofitall]

For those who’ve tested positive for Antiphospholipid antibodies (I’ve had two samples 12 weeks apart with raised IgM cardiolipin), what dose of clexane/inhixa/enoxaparin were you prescribed?

My new clinic seem to be keen on 20mg but my old clinic only used 20mg when it was empirical (best guess) treatment for recurrent implantation failure, and once they knew I tested positive for APS they increased the dose to 40mg from transfer. My new clinic are mainly private fertility specialists whereas my old clinic did have working obstetricians who I suspect had more experience with managing APS in actual pregnancy. I don’t want to risk bleeding but equally don’t want to be under treated.

[Chel91]

It's actually weight based so it depends on that. Most ladies fall into 40mg or 60mg depending on weight. 20mg would only be suitable if you were extremely petite.

[Endofitall in reply to Chel91]

Thank you that’s super helpful. I am quite light but probably with lots of unsuccessful IVF rounds and courses of pred under my belt have gained weight from when I started this process. I think my current clinic are just doing a 20mg standard empirical dose and not factoring in properly fact I’ve tested positive for APS. Will have to raise again with them. Thanks 🙏🏼