Failed ICSI fertilisation first attempt with only 1 mature egg

[Pomodoro2024]

Hi,

I just went through our first ICSI attempt and unfortunately only 1 egg has been retrieved and after ICSI there was no sign of fertilisation. I have low AMH (I am 36 years old and my AMH is 1.2) and my partner has male factor as well.

I went through a failed cycle in June with stimulation stopped at day 10 (very poor response). This time I went through a short cycle with 450 menopur.

I know that normally ICSI has a very good fertilisation rate (over 70%) and I was wondering if there is still hope after this failed attempt, or if this might be a symptom of other issues going on

Many thanks

[CyclingAddict]

Sorry to hear this. We also went through IVF-ICSI (due to male factor) and, after many failed transfers, finally had a positive result and I'm now 36 weeks pregnant. We did everything in our power before our last cycle to improve our chances (of course, a lot of it is down to luck). My husband managed to increase his sperm count from 1 million at its lowest to 10 million. He's really pretty healthy in general, but he did loads of research and took a cocktail of supplements everyday, took up running (some evidence suggests it increases sperm quality), and wore boxers with a cool pack in every night (they are called 'snowballs' ((lol)) on Amazon). I also started taking Q-10, changed my diet (I did more of a paleo diet to help with an immune condition), and we both didn't drink alcohol in the months leading up to treatment.

We ended up collecting more eggs than I got in my previous cycle and that, combined with my husband's improved sperm quality, may have made the difference.

Hope this helps and wishing you luck X

[Pomodoro2024 in reply to CyclingAddict]

Thank you so much for your advices and for sharing your experience. I keep all my fingers crossed

[JA-fnuk Partner Nurse Fertility Network UK]

Sorry to read your post and wanted to say thinking of you both Might be an idea to discuss your concerns with your clinic and see what they can suggest

Take care

Janet-Partner