Down regulation - blood test? - Fertility Network UK

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Down regulation - blood test?

Blueberryshrub profile image
3 Replies

Hi All, I am nearly at the end of the down regulation phase and will have my first scan next Tuesday to confirm if my ovaries have switched off. The reason why I had to go through the down regulation route is that my first IVF, which was a short protocol, failed miserably. I was bleeding and lost all of my uterine lining and also had high progesterone throughout the stims phase.

I feel like the down reg really helped with the pain I get from my endo - I do feel the difference but at the same time I have menopausal symptoms.

My first question is does your fertility clinic do blood test in addition to the scan, before you start taking the stims meds? When I asked my fertility clinic about the blood test, their answer was very vague. I dont think they will do the blood test which makes me very nervous.

And my second question is how quickly can womb, ovaries and pituitary gland recover after the down regulation? I will need to continue taking the agonist (synarel) during the stimulation phase to prevent the ovulation. Will this lower the chances of the fresh transfer, comparing this with the short protocol?

Thank you all and have a great weekend everybody!

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lulubelly1983 profile image
lulubelly1983

my clinic doesn’t do the blood test just the scan and check your uterus lining as a baseline, no it’s all thought out well in advance you keep switching off to stop ovulation and the stim drugs help build up your lining and then the progesterone which they’ll start you on after egg collection - this will make your uterus lining receptive to implantation while your eggs do what they’re going to for the next three to five days, you will stop down regulating drugs when you do your trigger shot 48hrs before egg collection, (they will keep you on the progesterone until 12wks of pregnancy as you won’t have a corpus lutuem to support a pregnancy then the placenta takes over) hopefully you'll have embryos/blastocyst to freeze too 👍🏻 hope this helps and good luck 🤞🏻 I’m 9dpt on medicated FET with 2 blastocyst transferred lots of history my 6th transfer 3 full cycles of ivf and 3 FET I have naughtily tested early because I can’t help myself and it’s positive 😍😍😍😍😍😍 🤞🏻🤞🏻🤞🏻🤞🏻🤞🏻🤞🏻just need to get to my scan now and see a heartbeat as my last cycle resulted in a missed miscarriage im so scared it’s going to be same

Blueberryshrub profile image
Blueberryshrub in reply tolulubelly1983

Thank you for sharing your story and I really really hope everything will work out for you this time and you will hear the best news soon 🤞🏻

Tnthketnf profile image
Tnthketnf

The NHS clinic always did blood tests. My private clinic abroad only sometimes. But for confirming downregulation both clinics did blood tests. I only had downregulation for FETs so I don't know how it impacts on the fresh transfer.

All the best!

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