Question re down regulation

[Lamagarden]

Hi all, Looking for some advice. We’ve just started our third round of IVF (1st: BFN 2nd: Chemical). On long protocol and taking buserlin for down regulation. Had my suppression scan on Tuesday (day 12 of down regs), was told my lining was still too thick and to continue on meds and have another suppression scan on Tuesday. Dr said it was nothing to worry about as sometimes it just takes longer than 10-14days to suppress. However, I feel concerned as to why it’s different this time. Maybe over thinking it but curious if anyone else has had the same experience. Also, my bleed (whilst on buserlin) was unusually long, a full 7 days. Told dr, they weren’t concerned.

On another note, I’ve now lost my voice and am worried that being poorly will negatively effect the IVF process. I think I’m very anxious now as it’s the third round. TIA.

[Joeysjourney]

Hello lovely, sorry you're feeling anxious, completely understand why.

I didn't have exactly the same experience but in the lead up to my recent FET I ended up down regging for 6-7 weeks. My body just kept trying to run its own cycle and I wasn't responding to the nasal spray. My lining just wouldnt play ball! I did have high oestrogen levels playing into the mix too tho.

Did they take any bloods?

No doubt you won't experience that as I think that's a bit extreme (typical me, I've had other weird things happen 😂), but our wee bodies do strange things and it's not unusual for you to need a little extra down reg to get your lining into the right place. I did get there in the end! If it hadn't started working I was going to shift onto a different type of down reg to try and kick start it so that's always an option.

The waiting is just a killer isn't it!

Hopefully all moves forward soon for you babe xxx

[Lamagarden in reply to Joeysjourney]

Thank you for you reply, best of luck with your FET. Feeling better to hear others have had the same experience. They didn’t do bloods but asked me to do a preg test.

[Purpledoggy]

This happened to me - first round 2 week downreg, second round I needed 3 weeks. I ovulated late on the second round (started buserelin 2 days after ovulation instead of a week) so that is probably why it took longer to downreg. My second round was actually the successful one so the extra week definitely did not hurt anything! xx

[Lamagarden in reply to Purpledoggy]

That’s so promising! I guess each round can be different. Thanks for your reply, has put my mind at ease.

[DianeArnold Partner Nurse Fertility Network UK]

Hi Lamagarden. Yes, hopefully a few more days will provide better results. This is not unsual, just a nuisance for you. Good luck! Diane

[Lamagarden in reply to DianeArnold]

Thank you Diane! That’s so good to know.