Hemostaseology is useful to identify reoccurring implantation failure?

[WaitingforGabriel]

Did anyone had Hemostaseology test (coagulation disorder) to identify reoccurring implantation failure? Did you achieve any success with treatment?

I suffer from reoccurring implantation failure and miscarriages. I need a way to identify and treat the cause. I appreciate your ideas.

[Tamaa]

Hi. Yes these tests are useful in finding out about the tendency towards blood clotting. Treatment is usually via aspirin and/or enoxaparin sodium injections and they lead to success.

[WaitingforGabriel in reply to Tamaa]

Thank you so much for your response.

[MrsOrangejuice]

Not sure it's exactly the same as my clinic and doctors didn't call it that, but I had a full blood panel done after a couple of early losses/chemicals post transfer and that included testing for 'sticky blood' which I think was thromobophilia and other blood clotting factors. Wasn't a particularly expensive test with my clinic but my GP was willing to do them. All came back clear so wasn't the reason for the losses for me, but my consultant said if they had come back as an issue they would have used specific blood thinners and not just aspirin.

[WaitingforGabriel in reply to MrsOrangejuice]

I am sorry to hear that you suffer the same. Are they planning to do other tests to identify the reason of losses?

[MrsOrangejuice in reply to WaitingforGabriel]

I asked my consultant to go through every test, investigation and option with me and explain whether they were relevant, worth it etc. He said as I'd had two laparoscopies and the last one hadn't even shown micro endometriosis there was no need to repeat, and one hysteroscopy ever was fine too and no need to repeat or do a 3D/aquascan. I asked about immune tests and he said his view was there was limited evidence for these and anyway I didn't have any other symptoms they'd normally expect with immune issues. On genetic testing he said he doubted it was our issue as we were mid to late 30s and had made embryos that looked good and had implanted twice. Plus he said when you test them you risk damaging them and may as well just defrost them once and transfer them. Sperm was fine so he said no reason to do fragmentation. But I guess check all those things with your clinic, even to rule them out? The only thing for me was progesterone as I'd always spotted before periods and before OTD on one transfer - changed to utrogestan (from cyclogest) and added lubion injections. The next transfer/first FET worked, but it could have been chance. I've since had a later loss on a fresh transfer and a BFN on a FET, so progesterone didn't solve everything, but still definitely worth checking as it's an easy fix. I'm now 7mnths pregnant naturally so I also know there was at least one egg and sperm that was genetically ok and that happened when I wasn't on any meds at all, so tbh I have less idea now what worked and didn't than when I started! But this may just give you a little hope too x

[WaitingforGabriel in reply to MrsOrangejuice]

Thank you for sharing your story. How nice to hear that you are 7m pregnant already. Congratulations!

[MrsOrangejuice in reply to WaitingforGabriel]

Thank you! I would just ask your clinic to go through all the different options with you and see if they think anything's worth doing. Turns out not really for me, and the consultant said just keep going with the transfers until one works, but it's so individual.