nac? Coenzymeq10 , gluthanione

hi all after a failed fet last month we are due to start a new cycle and back on the waiting list for new ivf treatment. Last cycle only produced 2 eggs .

had one fresh transfer day 3 which was my baby who i lost at 21 weeks. We then tried a fet which failed.

I only obtained 5 eggs 3 were immature and 2 which ive just stated above so not a great cycle. I have pcos and am 26 . Healthy bmi a good amh and no other issues.

They put me on 112.5 gonal f i think this was a very low dose. Hence the outcome.

I am thinking to take these supplements nac , co enzyme q10 and gluthanione . Can anyone tell me at what dose shall i take these .

My nac is 600 mg so how much shall i take a day?

Conenzyme q10? Is 600 mg

And gluthanione 1800 mg can any one tell me the doses you took and were effective for pcos/ivf

Or can u suggest any others

[DianeArnold Partner Nurse Fertility Network UK]

Hi Pcosivf. I would check i it’s ok with your specialist first. Remember your body has to sort everything out and you don’t want any inactions. Good luck. Diane

[happypupp]

Hi, NAC is a precursor to glutathione and more affordable so you probably don't need to take both. I was on NAC 600mg x 2 /day until EC and reduced to 1/day post EC for FET

There are studies on myo-inositol with PCOS women. It All Starts With The Egg book talks about it more.

I went on a private fertility coaching programme by a functional nutrition specialist for 4 months, and her support was priceless. Helped us adjust our diet and supplementation to navigate the IVF journey. Maybe you could speak to one too? Ours does single consultations

[Elmo13 in reply to happypupp]

Hi there, so sorry for butting in on this but would you mind PM’ing me details of the specialist you used? Thanks x

[Kilk22 in reply to happypupp]

hi, just curious about NAC. I'm taking it but I don't have PCOS. I want to help my egg quality for ivf in the new year. Is it good for egg quality too or specifically for pcos? I don't want to mess up my chances xx thanks x

[happypupp in reply to Kilk22]

Kilk22 I don't have PCOS but I've been on NAC 600mg since Jan/Feb and upped to 1200mg since April/May. It's shown to improve egg quality in clinical studies and I have not seen any adverse effect on my EC results though all my 3 x EC cycles have been positive and I banked 1 or more euploid embryos per cycle, I'm 43 years old. I have not given a live birth though, just had one euploid FET.

This page sums up NAC nicely with references to relevant studies:

miscarriagehopedesk.org/nac...

[Kilk22 in reply to happypupp]

Thanks so much. Great to get that information. I am 41 so want to give it my best shot with my own eggs. I hope you have success with your frozen embaby 🫶🏼🤞🏽🤞🏽🤞🏽 2024 be kind to us all 🙌🏽

[Nakijo in reply to happypupp]

Hi Konyago, just checking if you got your BFP and kindly share the supplements you took

[Eloquentia]

Hi! I am very sorry that the first cycle of IVF didn't work I have PCOS too. Our clinic recommended Proxeed for both me and my other half, we also took CoQ10 in the form of ubiquinol, Vitamin D spray and probiotics. Because of my PCOS I also took myo-inositol, which I have found to help me get more regular periods and process sugar better. Good luck!

[Hidden in reply to Eloquentia]

Hello thankyou , for your response what probiotics did you take?

[Eloquentia in reply to Hidden]

I took Lactoflor oral probiotics and canesfloor vaginal ones.