Run out of DHEA 4 days before retriev... - Fertility Network UK

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Run out of DHEA 4 days before retrieval, buy more?

Eggfreezing36 profile image
12 Replies

Hi all,

I am going to run out of DHEA 3-4 days before my egg retrieval and the amount I have (8 pills or so) means I need to go down to 50mg a day not 75mg to make it last as many days as possible.

I know this is my own fault for being disorganised and not checking the bottle, pfft.

I have asked my clinic is this OK or will it cause a negative effect and they said it SHOULD be OK - they usually advise taking DHEA up until the day before egg collection - but they don't have any research to say, so they can't really advise me (I guess they have to say this from a legal perspective).

Does anyone here have any advice? I could get a prescription from my clinic - it would mean paying £100 for just a few days of pills. I am minded not to, as surely a drop in testosterone levels can not negatively impact? But in the absence of a definite answer from my clinic, thought I would ask :)

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Eggfreezing36
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12 Replies
Tarasunny profile image
Tarasunny

I think you should be fine to stop. I'd imagine you'd already have all the benefit you are going to get from the DHEA by then. I'm sure I stopped the day before I started stims.

finup0321 profile image
finup0321 in reply toTarasunny

I agree, I also stopped DHEA right before stims and I would start again after retrieval for future rounds. My consultant suggested it, he said it may interfere with the stims actually working. DHEA does its work in the 2-3 months leading up to stims, as that’s when egg development happens. Unless you plan on doing more retrievals, then it sounds like you should be good!

Eggfreezing36 profile image
Eggfreezing36 in reply tofinup0321

Thanks! My clinic said they want me to stop the day before the retrieval, so I was just worried about the drop in testosterone doing something to the eggs. But the clinic can't comment on that! Now my other q is: do I carry on taking 3 pills (75 mg) a day in which case I will stop like 4 days before retrieval, or do I go down to 2 pills (50mg) a day to even out the dose? Leaning towards the latter. So many decisions lol

finup0321 profile image
finup0321 in reply toEggfreezing36

I would definitely ask the clinic. They’ll know what’s best for your protocol.

Eggfreezing36 profile image
Eggfreezing36 in reply tofinup0321

Thanks. I didn't ask re 3 a day vs 2 a day but they said they can't advise on whether stopping early or not will have a negative outcome as they don't actually know. Helpful lol.

Eggfreezing36 profile image
Eggfreezing36 in reply toTarasunny

Thanks! My clinic said to carry on throughout stims but yes I don't think I will buy more for the sake of a few days. Now just to decide: do I carry on taking 3 pills (75 mg) a day in which case I will stop like 4 days before retrieval, or do I go down to 2 pills (50mg) a day to even out the dose? Leaning towards the latter. So many decisions lol

Tarasunny profile image
Tarasunny in reply toEggfreezing36

Yeah that's a good idea. I think I'd probably go down to 2 a day eek them out a bit more if that would make you feel more comfortable.

Football61 profile image
Football61 in reply toEggfreezing36

Definitely even out the dose! 👍

Koala365 profile image
Koala365

You can usually get some micronised DHEA shipped from Iherb in just a few days if you Google it if you are worried. I don't imagine it will make much difference bit for peace of mind I would probably get some so that I felt I had done everything I could. Surprised they are prescribing it for £100 though. I thought it wasn't authorised in the UK hence we have to order it from the USA.

Eggfreezing36 profile image
Eggfreezing36 in reply toKoala365

Yes it's about £80 for 100 tablets from my pharmacy. i have a prescription from my clinic but I am just struggling to see at this late stage a small drop in testosterone from levelling off to 2 pills per day and stopping a few days before having a negative impact? My clinic won't advise either way...

Koala365 profile image
Koala365 in reply toEggfreezing36

How soon do you need them? It looks as though you can get 90 capsules of 25mg micronised DHEA for £12.58 plus postage from Iherb for delivery in the UK between 1 and 6 September which might be worth it for a top up. I also had my clinic give me a blood test to establish what my DHEA levels were to see if they were now up to the level of a woman around 25 years old which I think is what they are aiming for in older women.

Eggfreezing36 profile image
Eggfreezing36 in reply toKoala365

My egg retrieval is 30 August so too late. I think I will leave it...i have gone down to 2 pills per day from a few days back and that gets me to Sunday then I am finished from Monday and my egg retrieval is on Weds (unless gets pushed back but hasn't the last two times so doubt it). Surely it can't impact badly?!

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